Prevention of Atopic Disease: Environmental Engineering Utilizing Antenatal Antigen Avoidance and Breast Feeding
Atopic disease is a common cause of recurrent and chronic illness in young children. Its incidence appears to have increased in the last 15–20 years. The physical, psychological and health costs of atopic disease have prompted attempts at prevention. Much of the recent work has focussed on eczema, the most common manifestation of atopy. Heredity, immunoregulatory abnormalities, environmental factors and food hypersensitivity are considered to be important pathogenetic factors.1–5 In this selective review, the concept of environmental engineering to overcome the handicap of hereditary predisposition is proposed and developed. Eczema is used as the prototype of atopic disease.
KeywordsDust Histamine Smoke Macromolecule Tetanus
Unable to display preview. Download preview PDF.
- 5.R.K. Chandra, “Food Allergy,” Nutrition Research Education Foundation, St. John’s (1986).Google Scholar
- 11.U.M. Saarinen, Prophylaxis for atopic disease. Role of infant feeding, Clin. Rev. Allergy 2:151–67 (1984).Google Scholar
- 12.R.K. Chandra, S. Puri, C. Suraiya, and P.S. Cheema, Influence of maternal food antigen avoidance during pregnancy and lactation on incidence of atopic eczema in infants, Clin. Allergy Vol. 16 (in press) (1986).Google Scholar