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Loss of Sensory and Motor Neurons After Nerve Injury in Young and Adult Rats

  • Henning Schmalbruch

Abstract

The concept of Wallerian degeneration implies that the distal part of a cut axon is lost whereas the neuron survives. There are, however, exceptions from this rule, and in particular immature neurons may die after axotomy (Gudden, 1870; Lieberman, 1974). Hence, functional deficits after nerve repair may not only be due to aberrant reinnervation but also to neuron death. Axotomy-induced neuron death has also attracted interest because it relates to the neuronotrophic action of the target.

Keywords

Dorsal Root Ganglion Sciatic Nerve Sensory Neuron Ventral Root Motor Axon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Henning Schmalbruch
    • 1
  1. 1.Institute of NeurophysiologyUniversity of Copenhagen, Panum InstituteKøbenhavn NDenmark

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