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Antagonists, Dualists, and Kappa Agonists

  • Chapter
Opioid Analgesics

Abstract

The aim of this chapter is to bring together data on opioid ligands that (1) antagonize the actions of morphine and its surrogates, (2) possess both agonist and antagonist properties, and (3) possess the unique pharmacological profile of the so-called kappa (κ) agonists. The majority of these compounds fall within the morphine, morphinan, or benzomorphan groups of opioid ligands (Chapters 2, 3, and 4). The topic of narcotic antagonists and dualists has been extensively reviewed up to 1976(1) and only a resumé of the earlier work is presented here.

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  1. University of Bath, Bath, UK

    Alan F. Casy & Robert T. Parfitt

  2. Canberra College of Advanced Education, Belconnen, ACT, Australia

    Robert T. Parfitt

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Casy, A.F., Parfitt, R.T. (1986). Antagonists, Dualists, and Kappa Agonists. In: Opioid Analgesics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0585-7_12

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