Abstract
This book deals with substances commonly described as analgesics or analgetics that alleviate or abolish pain without at the same time inducing loss of consciousness. Their site of action is essentially within the central nervous system whereby they are distinguished from pain-relieving drugs such as aspirin and other anti-inflammatory agents that act at peripheral locations. Their central actions are depressant but they may be differentiated from general agents of this description such as barbiturates and anesthetics in that they influence specific sites, those concerned with the appreciation of pain and the control of respiration being the most notably affected. Nowadays a distinction is made between the terms opiate and opioid as applied to central analgesics. The former term refers to agents derived from opium or one of its constituents, while the latter is the more general term for agents with morphinelike properties; hence, the title of this book, Opioid Analgesics.
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Casy, A.F., Parfitt, R.T. (1986). Introduction. In: Opioid Analgesics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0585-7_1
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