Effects of Morphine Opiates on Immune Function

  • Hikmet Koyuncuoğlu
  • Mehmet Güngör


The general anesthesia and surgery on the morphine opiate addicts,in which total blood volume and blood cell mass had been found to be less than normal, were more problematic and complicated than on the patients and prisoners in similar health conditions (Williams and Oberst, 1946; Isbell, 1947; Eiseman et al., 1964). There is substantial evidence that opiate addicts suffer from a mortality rate considerably higher that what would be expected in relation to their age. The follow-up studies of opiate addicted persons discharged from the treatment institutions reveal that a marked proportion died shortly after discharge although they were mostly young adults. Among the causes of death found in postmortem examinations the major medical complications of opiate addiction mostly related to the use and administration routes such as abscesses, cellulitis, endocarditis, hepatitis, pneumonia, septic pulmonary embolism, tetanus, thrombophlebitis etc. were called up (Tolentino et al., 1961; Cherubin, 1967; Louria et al., 1967; Cherubin et al., 1968; Espiritu and Medina, 1980; Tarr, 1980; Sequeira et al., 1982) ignoring the fact that opiate addicts are highly prone to infectious diseases and death (Cherubin, 1967).


Growth Hormone Luteinizing Hormone Anorexia Nervosa Growth Hormone Release Narcotic Analgesic 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Hikmet Koyuncuoğlu
    • 1
  • Mehmet Güngör
    • 1
  1. 1.Department of Pharmacology and Clinical PharmacologyIstanbul Medical FacultyÇapa, IstanbulTurkey

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