Endorphins: A Link Between Personality, Stress, Emotions, Immunity, and Disease ?

  • George S. Solomon
  • Neil Kay
  • John E. Morley


A growing body of evidence — clinical and experimental, human and animal — that has been accumulating over the last 20 years since Solomon and Moos’ then-speculative theoretical integration of emotions, immunity and disease (1) pointed to experiential influences on immune function mediated by the central nervous system and the neuroendocrines, neurotransmitters, and neuropeptides controlled by it. The emerging field of psychoneuroimmunology (2), also referred to as neuroimmunomodulation (3), has rapidly expanded over the last few years due, in part, to the discovery that the endogenous opiods (endorphins), which are released from the anterior pituitary during stress, are potent immune system modulators.


Growth Hormone Opioid Peptide Growth Hormone Response Maternal Separation Hypothalamic Lesion 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • George S. Solomon
    • 1
    • 2
  • Neil Kay
    • 1
    • 2
  • John E. Morley
    • 1
    • 2
  1. 1.Education and Clinical Center Sepulveda VA Medical Center (11E)Geriatric ResearchUSA
  2. 2.Minneapolis VA Medical Center MinneapolisUSA

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