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Sleep Facilitating Effects of Vitamin B12

  • Hiroshi Itoh
  • Motohiro Ozone
  • Mitsuo Sasaki

Abstract

Recent experiments (Kamgar-Paris 1983, Okawa 1990) have shown that vitamin B12 (Vit. B12) has therapeutic effects on circadian rhythm sleep disorders, such as delayed sleep phase syndrome (DSPS) and non-24 hours sleep wake rhythm disorder (Non-24). Regarding the mechanisms of therapeutic action of Vit. B12 on circadian rhythms sleep wake disorders, many study consider its effects on the phase or period of circadian rhythms and on photo sensitivity. But at the present time the definite mechanisms of action are still unclear.

Keywords

Sleep Onset Sleep Latency Slow Wave Sleep Sleep Parameter Delay Sleep Phase Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Hiroshi Itoh
    • 1
  • Motohiro Ozone
    • 1
  • Mitsuo Sasaki
    • 1
  1. 1.Department of PsychiatryThe JIKEI University School of MedicineTokyo 105Japan

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