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Treatment Intensification in Germ-Cell Tumours

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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2

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Abstract

Germ-cell tumours are rare diseases. However they occur in young patients and their prognosis was unfavourable before the introduction of cisplatin in chemotherapy regimens. Cisplatin based chemotherapy followed by the surgical removal of residual disease is the standard treatment of these tumours (1). Different prognostic classifications or models allow to assign patients in good-risk or poor-risk groups (2). The standard chemotherapy regimen in the good-risk patients group is either three cycles of a combination of cisplatin, etoposide and bleomycin (BEP) or four cycles of combination of etoposide and cisplatin (EP) (1).

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Author information

Authors and Affiliations

  1. Department of Medical Oncology, Centre Léon Bérard, 28 rue Laënnec, 69373, Lyon cedex 08, France

    Jean-Pierre Droz & Pierre Biron

  2. Centre Val d’Aurelle Paul-Lamarque, 326 rue des Apothicaires, Parc Euromédecine, 34298, Montpellier cedex 5, France

    Stéphane Culine

  3. Department of Biostatistics, Institut Gustave Roussy, rue Camille Desmoulins, 94805, Villejuif cedex, France

    Andrew Kramar

Authors
  1. Jean-Pierre Droz
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  2. Pierre Biron
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  3. Stéphane Culine
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  4. Andrew Kramar
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Editor information

Editors and Affiliations

  1. Free University, Amsterdam, The Netherlands

    H. M. Pinedo

  2. Netherlands Cancer Institute, Amsterdam, The Netherlands

    J. H. Schornagel

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© 1996 Springer Science+Business Media New York

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Droz, JP., Biron, P., Culine, S., Kramar, A. (1996). Treatment Intensification in Germ-Cell Tumours. In: Pinedo, H.M., Schornagel, J.H. (eds) Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0218-4_22

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  • DOI: https://doi.org/10.1007/978-1-4899-0218-4_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0220-7

  • Online ISBN: 978-1-4899-0218-4

  • eBook Packages: Springer Book Archive

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