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Lipoxygenases of Mice and Men

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Eicosanoids

Part of the book series: NATO ASI Series ((NSSA,volume 283))

Abstract

Seven years have elapsed since the cloning of the cDNA for the first mammalian lipoxygenase and the deduced primary structure (Matsumoto et al., 1988; Dixon et al., 1988). Here, a brief comparative overview of the molecular properties of human and mouse lipoxygenases will be presented. Although each of the human lipoxygenases were isolated and systematically characterized prior to the corresponding murine homologs it became necessary to evaluate their relatedness in view of our present targeted lipoxygenase gene inactivation experiments in mice.

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© 1996 Springer Science+Business Media New York

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Funk, C.D. (1996). Lipoxygenases of Mice and Men. In: Folco, G.C., Samuelsson, B., Maclouf, J., Velo, G.P. (eds) Eicosanoids. NATO ASI Series, vol 283. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0200-9_2

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  • DOI: https://doi.org/10.1007/978-1-4899-0200-9_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-0202-3

  • Online ISBN: 978-1-4899-0200-9

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