Neuronal Activity of Monkey Pedunculo-Pontine Tegmental Nucleus Area I

Activity Related to Voluntary Arm Movements
  • Masaru Matsumura
  • Katsushige Watanabe
  • Chihiro Ohye
Part of the Advances in Behavioral Biology book series (ABBI, volume 47)


Anatomical studies have revealed dense connections between the pedunculopontine tegmental nucleus (PPN) and the basal ganglia (Figure 1). In primates, PPN receives massive afferents from the two output structures of the basal ganglia, that is, the substantia nigra pars reticulata and the internal pallidum. In turn, PPN projects profusely to the substantia nigra pars compacta and the subthalamic nucleus (Filion and Harnois, 1978; Harnois and Filion, 1980; Harnois and Filion, 1982; Parent and Hazrati, 1995). These ascending projections were found both ipsilaterally and contralaterally (Lavoie and Parent, 1994b). The existence of cerebello-tegmental projections, which are ipsilateral collaterals of the cerebello-thalamic projection, was also reported (Hazrati and Parent, 1992). Motor cortex (area 4) also sends fibers to PPN (Hartmann-Von Monakow et al., 1979; Moon Edley and Graybiel, 1983). PPN is a part of the mesencephalic locomotor region, from which locomotor movements are induced by its electrical stimulation (Garcia-Rill, 1986; Garcia-Rill, 1991).


Basal Ganglion Squirrel Monkey Subthalamic Nucleus Pedunculopontine Nucleus Pedunculopontine Tegmental Nucleus 


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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Masaru Matsumura
    • 1
  • Katsushige Watanabe
    • 1
  • Chihiro Ohye
    • 1
  1. 1.Department of NeurosurgeryGunma University School of MedicineMaebashi, Gunma, 371Japan

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