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B-Cell Sites in the HIV Glycoproteins

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Book cover Immunology of HIV Infection

Abstract

HIV, like other lentiviruses, has the capacity to direct the synthesis of a large number of different proteins. Some of these proteins participate in the formation of virus particles, whereas other proteins of a nonstructural nature appear in infected cells and may be released by secretion or in connection with a possible death of such cells. Each of these different proteins has a varying number of immunogenic sites, which may elicit humoral as well as cell-mediated responses. An acute infection with HIV as a consequence can lead to the mobilization of a large spectrum of immune responses. It is a daunting task to define the dynamics and specificities of these reactions. A considerable amount of information has already accumulated in this field, but more knowledge is needed to provide a comprehensive understanding of the complete relationship. There are three major contexts in which knowledge of HIV immunobiology is applicable.

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Authors and Affiliations

  1. Microbiology and Tumorbiology Center, Karolinska Institute, S-171 77, Stockholm, Sweden

    Ewa Björling & Erling Norrby

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  1. Ewa Björling
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  2. Erling Norrby
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  1. University of California, Irvine, California, USA

    Sudhir Gupta M.D., Ph.D.

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© 1996 Springer Science+Business Media New York

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Björling, E., Norrby, E. (1996). B-Cell Sites in the HIV Glycoproteins. In: Gupta, S. (eds) Immunology of HIV Infection. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0191-0_3

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  • DOI: https://doi.org/10.1007/978-1-4899-0191-0_3

  • Publisher Name: Springer, Boston, MA

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