Some Actions of Taurine on Ionic Currents of Myocardial Cells and Myometrial Cells
The sulfur amino acid taurine has been reported: (i) to be a positive inotropic (cardiotonic) agent in failing hearts, in both animals and human; (ii) to be depleted in myocardial cells in ischemic heart disease; and (iii) to cause heart failure when deficient in diet of animals (e. g., cats) that cannot synthesize taurine. The taurine content of the heart is elevated in patients and animals with congestive heart failure1. Taurine has been used as a treatment for patients with congestive heart failure (e. g., 3 g per day) by Dr. Azuma et al. In Japan and Korea, soft drinks (e. g., soda pop and fruit drinks) that contain taurine (e. g., 1 g) as an additive are widely available.
KeywordsMyocardial Cell Pipette Solution Hold Potential Myometrial Cell Taurine Content
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