Taurine 2 pp 203-212 | Cite as

Long-Lasting Hypoxic Preservation of Porcine Kidney Cells

Beneficial Effect of Taurine on Viability and Metabolism in a Simplified Transplantation Model
  • Peter Wingenfeld
  • Ute Gehrmann
  • Stefan Strübind
  • Thomas Minor
  • Wolf Isselhard
  • Dietrich Volker Michalkl
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)

Abstract

In the field of transplantation medicine one of the determining factors for the outcome of the transplanted organ is the cellular deterioration due to hypoxia and reoxygenation and the protection against it. Frequently the hypoxic storage of the removed organ limits the possibility of successful transplantation. The hypoxic cell damage due to insufficient organ preservation is a major cause for the loss or the dysfunction of transplanted organs like hearts and kidneys2, 5, 6, 15, 17.

Keywords

Peroxide HPLC Ischemia EDTA Lactate 

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Peter Wingenfeld
    • 1
  • Ute Gehrmann
    • 1
  • Stefan Strübind
    • 1
  • Thomas Minor
    • 2
  • Wolf Isselhard
    • 2
  • Dietrich Volker Michalkl
    • 1
  1. 1.Department of PediatricsUniversity of CologneCologneGermany
  2. 2.Institute for Experimental MedicineUniversity of CologneCologneGermany

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