Taurine 2 pp 165-171 | Cite as

Taurine and Water Channels are Co-Localized in Renal Tubule Cells and Other Tissues

Immunocytochemical Studies in Rats
  • M. Amiry-Moghaddam
  • E. A. Nagelhus
  • P. Agre
  • S. Nielsen
  • O. P. Ottersen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)


One of the best established roles of taurine is that of an osmoregulator7. Many cell types have been shown to sustain a loss of taurine upon exposure to hypoosmotic stress11 while an increased uptake of this amino acid can be induced by hyperosmotic conditions12. The latter effect has been demonstrated in renal cells in culture, thus supporting the notion that taurine acts as an organic osmolyte in the kidney along with polyhydric alcohols and methylamines5.


Gold Particle Water Channel Tubule Cell Intercalate Cell Collect Duct 


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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • M. Amiry-Moghaddam
    • 1
  • E. A. Nagelhus
    • 1
  • P. Agre
    • 2
  • S. Nielsen
    • 3
  • O. P. Ottersen
    • 1
  1. 1.Department of Anatomy, Institute of Basic Medical SciencesUniversity of OsloOsloNorway
  2. 2.Johns Hopkins University School of MedicineBaltimoreUSA
  3. 3.Department of Cell Biology, Institute of AnatomyUniversity of AarhusAarhusDenmark

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