Zinc and Copper in Breast Cancer
Present incidence of breast cancer as well as its ratio to all cancer ranks Slovakia to European countries with high and still increasing incidence of breast cancer. Mortality rates became stabilised in the recent time but evidently increasing incidence of breast cancer is observed especially in lower age groups. Zinc and copper are essential trace elements that play important roles in different biochemical reactions. Relevance of zinc to cellular growth is well known. In recent years, their disbalances were linked to chronic disease etiology due to antioxidant properties. Moreover, zinc affects immunological properties and acts together with copper as cofactor of Cu, Zn-superoxide dismutase (SOD). This enzyme protects cells and their important components against free radical damage.
KeywordsBreast Cancer Menopausal Status Essential Trace Element Benign Breast Disease Serum Copper
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F. Cavallo, M.G. Gerber, E. Marubini et al., Cancer
, 738–745 (1991).CrossRefGoogle Scholar
I. Yücel, F. Arpaci, A. Özet et al., Biol. Trace Elem. Res.
, 31–38 (1994).CrossRefGoogle Scholar
G.D. Kanias, E. Kouri, H. Arvaniti et al., Biol. Trace Elem. Res.
, 363–370 (1991).CrossRefGoogle Scholar
M. Faber, C. Coudray, H. Hida et al., Biol. Trace Elem. Res.
, 117–123 (1995).CrossRefGoogle Scholar
J. Garofalo, H. Ashikari, M.L. Budrick et al., Cancer
, 793–794 (1980).Google Scholar
T. Magálová, A. Brtková, A. Béderová et al., Biol. Trace Elem.Res.
, 225–235 (1994).CrossRefGoogle Scholar
Y. Niwa, O. Iizawa, K. Ishimoto et al., Am.J.Pathol.
, 312–320 (1993).Google Scholar
M.R. De la Torre, A. Casado and M.E. López-Fernández, Experientia
, 854–856 (1990).CrossRefGoogle Scholar
E.D. Harris, J.Nutr.
, 636–640 (1992).Google Scholar
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