Abstract
Nitric oxide (NO) has been ascertained to play an important role in signal transduction in the central nervous system, functioning as a short-lived modulator and/or second messenger1,32. There is a functional link between NO and glutamatergic neurotransmission. NO is involved in synaptic plasticity, for example, in long-term potentiation, memory and learning, in the hippocampus4, which phenomena represent physiological effects of glutamate as a transmitter. Glutamate also participates in the development of ischemic brain injury, and therefore, NO is likely to be associated with mechanisms of neuronal damage4.
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Saransaari, P., Oja, S.S. (1998). Effects of NO-Generating Compounds on the Uptake and Release of Taurine in the Mouse Brain. In: Schaffer, S., Lombardini, J.B., Huxtable, R.J. (eds) Taurine 3. Advances in Experimental Medicine and Biology, vol 442. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0117-0_44
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DOI: https://doi.org/10.1007/978-1-4899-0117-0_44
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