Effects on Female Fertility and Germinal Cells in Prepubertal and Adult Rats (Rattus norvegicus) after X-Ray Irradiation
In this work we analise the effects of ionizing radiation in prepubertal and adult female rats, using as parameters, implantation sites, embryonic loss, and synaptonemal complex (SC) analysis of the female F1 of the pregnant rats. Our preliminary results show a decrease statisticaly significant in fertility of irradiated groups, but cytogenetic analysis did not shown any inherited damage atributed to radiation. At the same time, our results seem to indicate a higher resistance of oocytes from prepubertal rats and support the possible use of GnRH agonists as oestrus cycle supressors to turn adult rats into gonadal quiescence.
KeywordsGnRH Agonist Synaptonemal Complex Mouse Oocyte Irradiate Group Embryonic Loss
Unable to display preview. Download preview PDF.
- Jarrell, J., Young Lai, E.V., Barr, R., McMahon, A., Belbeck, L., O’Connell, G., 1986, An analysis of the effects of increasing doses of ionizing radiation to the exteriorized rat ovary on follicular development, atresia and serum gonadotropin levels. Am. J. Obstet. Gynecol, 154: 306–309.PubMedGoogle Scholar