Single Day Treatment — A Feasible Tool in Revealing Not Dependent on Maternal Toxicity Teratogenic Potential
The aim of this study is to explore the applicability of single day treatment for separation of development effects as an intrinsic property from those related to maternal toxicity. The fungicides paclobutrazole and benomyl were administered to pregnant rats on days 6 to 15 and on 7, 9, 11 and 13 day of gestation. After a single treatment higher percentage of fetuses were with external and visceral anomalies.
KeywordsFetal Weight Cleave Palate Skeletal Anomaly Malformation Rate Maternal Body Weight
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