In Vivo Survival of Human Energy-Replete Carrier Erythrocytes
Erythrocytes have been proposed as carriers of encapsulated therapeutic agents. Encapsulation of therapeutic agents within erythrocytes with a normal mean cell life range of 89 to 131 days (normal half-life of 19 to 29 days) should limit the vascular clearance of the administered drug thus reducing the dosage and frequency of therapeutic interventions.
KeywordsAdenosine Deaminase Surface Counting Citrate Dextrose 51Cr Activity Carrier Erythrocyte
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