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Rat Carrier Erythrocytes Circulate and Arrive to Organs

  • F. J. Alvarez
  • J. A. Jordán
  • J. C. Murciano
  • J. Luque
  • A. Herráez
  • J. C. Díez
  • M. C. Tejedor

Abstract

Different delivery systems are currently used in therapy. They have the advantage of protecting the active substance from rapid clearance and avoiding toxic side effects. Among the many carrier systems proposed12, RBCs have many desirable properties: they are naturally biodegradable and may stay in circulation over prolonged periods of time11,25; RBCs are easily obtainable and large amounts of material can be entrapped in a small volume of cells by hypotonic dialysis; autologous cells elicit little or no immune response7,16,20.

Keywords

Carbonic Anhydrase Human Erythrocyte Encapsulation Process Sodium Chromate Organ Uptake 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • F. J. Alvarez
    • 1
  • J. A. Jordán
    • 1
  • J. C. Murciano
    • 1
  • J. Luque
    • 1
  • A. Herráez
    • 1
  • J. C. Díez
    • 1
  • M. C. Tejedor
    • 1
  1. 1.Department of Biochemistry and Molecular BiologyUniversity of AlcaláAlcalá de HenaresSpain

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