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Abstract

Rubella (German measles) generally is a mild viral illness that may be associated with fever, lymphadenopathy, and a generalized rash. An estimated 50% or more of infections are subclinical. The most serious consequences of rubella occur in infants of women infected early in pregnancy. These infants are at high risk for congenital rubella syndrome (CRS), which may include a number of abnormalities.

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References

  1. Alford, C A, Studies on antibody in congenital rubella infections, Am. J. Dis. Child. 110:455–463 (1965).

    Google Scholar 

  2. Balfour, H. H., JR., Groth, K. E., Edelman, C. K., Amren, D. P., Best, J. M., And Banatvala, J. E., Rubella viraemia and antibody responses after rubella vaccination and reimmunization, Lancet 1: 1078–1080 (1981).

    Google Scholar 

  3. Banatvala, J. E., Best, J. M., O’Shea, S., And Dudgeon, J. A., Persistence of rubella antibodies after vaccination: Detection after experimental challenge, Rev. Infect. Dis. 7: S86 - S90 (1985).

    Google Scholar 

  4. Banatvala, J. E., Potter, J., And Best, J. M., Interferon response to Sendai and rubella viruses in human foetal cultures, leukocytes and placental cultures, J. Gen. Virol. 13:193–201 (1971).

    Google Scholar 

  5. Barnes, E. K., Altman, R., Austin, S. M., And Dougherty, W. J., Joint reactions in children vaccinated against rubella. Study II: Comparison of three vaccines, Am. J. Epidemiol. 95:59–66 (1972).

    Google Scholar 

  6. Bart, K. J., Orenstein, W. A., Preblud, S. R., And Hinman, A. R., Universal immunization to interrupt rubella, Rev. Infect. Dis. 7:S177–S184 (1985).

    Google Scholar 

  7. Bart, K. J., Orenstein, W. A., Preblud, S. R., Hinman, A. R., Lewis, F. L., JR., And Williams, N. M., Elimination of rubella and congenital rubella from the United States, Pediatr. Infect. Dis. 4: 14–21 (1985).

    Google Scholar 

  8. Bart, S. W., Stetler, H. C., Preblud, S. R., Williams, W. A., Orenstein, W. A., Bart, K. J., Hinman, A. R., And Herrmann, K. L., Fetal risk associated with rubella vaccine: An update, Rev. Infect. Dis. 7:595-S102 (1985).

    Google Scholar 

  9. Behan, P. O., Diffuse myelitis associated with rubella vaccination, Br. Med. J. 1:166 (1977).

    Google Scholar 

  10. Best, J. M., Banatvala, J. E., Morgan-Capner, P., And Miller, E., Fetal infection after maternal reinfection with rubella: Criteria for defining reinfection, Br. Med. J. 299: 773–775 (1989).

    Google Scholar 

  11. Birch, C. J., Glaun, B. P., Hunt, V., Irving, L. G., And Gust, I. D., Comparison of passive haemagglutination and haemagglutination-inhibition techniques for detection of antibodies to rubella virus, J. Clin. Pathol. 32:128–131 (1979).

    Google Scholar 

  12. Bottinger, M., And Heller, L, Experiences from vaccination and revaccination of teenage girls with three different rubella vaccines, J. Biol. Stand. 4:107–114 (1976).

    Google Scholar 

  13. Briss, P. A., Fehrs, L. J., Hucheson, R. H., And Schaffner, W., Rubella among the Amish: Resurgent disease in a highly susceptible community, Pediatr. Infect. Dis. J. 11:955–959 (1992).

    Google Scholar 

  14. Brody, J. A., Sever, J. L., Mcalister, R., Schiff, G. M., And Cutting, R., Rubella epidemic on St. Paul Island in the Pribilofs, 1963. I. Epidemiologic, clinical, and serologic findings, J.A.M.A. 191:619–623 (1965).

    Google Scholar 

  15. Buescher, E. L., Behavior of rubella virus in adult populations, Arch. Ges. Virusforsch. 16:470–476 (1965).

    Google Scholar 

  16. Buimovici-Klein, E., And Cooper, L. Z., Cell-mediated immune response in rubella infections, Rev. Infect. Dis. 7:S123–128 (1985).

    Google Scholar 

  17. Buimovici-Klein, E., Lang, R. B., Ziring, P. R., And Cooper, L. Z., Impaired cell-mediated immune response in patients with congenital rubella: Correlation with gestational age at time of infection, Pediatrics 64: 620–626 (1979).

    Google Scholar 

  18. Centers For Disease Control, Rubella-United States 19771979, Morbid. Mortal. Week. Rep. 28:374–375 (1979).

    Google Scholar 

  19. Centers For Disease Control, Rubella in Air Force recruits-Texas, 1977–1978, Morbid. Mortal. Week. Rep. 29:73–75 (1980).

    Google Scholar 

  20. Centers For Disease Control, Rubella outbreak in an office building-New Jersey, Morbid. Mortal. Week. Rep. 29:517–518 (1980).

    Google Scholar 

  21. Centers For Disease Control, Rubella and congenital rubella syndrome-United States, 1983–1984, Morbid. Mortal. Week. Rep. 33:528–531 (1984).

    Google Scholar 

  22. Centers For Disease Control, Rubella in colleges-United States, 1983–1984, Morbid. Mortal. Week. Rep. 34:228–231 (1985).

    Google Scholar 

  23. Centers For Disease Control, Rubella outbreaks in prisons-New York City, West Virginia, California, Morbid. Mortal. Week. Rep. 34:615–618 (1985).

    Google Scholar 

  24. Centers For Disease Control, Measles prevention: Recommendations of the Immunization Practices Advisory Committee (Acip), Morbid. Mortal. Week. Rep. 38:1–18 (1989).

    Google Scholar 

  25. Centers For Disease Control, Rubella vaccination during pregnancy-United States, 1971–1988, Morbid. Mortal. Week. Rep. 38:289–293 (1989).

    Google Scholar 

  26. Centers For Disease Control, Rubella prevention: Recommendations of the Immunization Practices Advisory Committee (Acip), Morbid. Mortal. Week. Rep. 39:1–18 (1990).

    Google Scholar 

  27. Centers For Disease Control, Increase in rubella and congenital rubella syndrome-United States, 1988–1990, Morbid. Mortal. Week Rep. 40:93–99 (1991).

    Google Scholar 

  28. Centers For Disease Control, Outbreaks of rubella among the Amish-United States, 1991, Morbid. Mortal. Week Rep. 40:264–265 (1991).

    Google Scholar 

  29. a. Centers For Disease Control, Rubella and congenital rubella syndrome-United States, January 1,1991-May 7,1994, Morbid. Mortal. Week. Rep. 43:391, 397–401 (1994).

    Google Scholar 

  30. Chantler, J. K., Ford, D. K., And Tingle, A. J., Persistent rubella infection and rubella associated arthritis, Lancet 1:13231325 (1982).

    Google Scholar 

  31. Chantler, J. K., Tingle, A. J., And Petty, R., Persistent rubella virus infection associated with chronic arthritis in children, N. Engl. J. Med. 313:1117–1123 (1985).

    Google Scholar 

  32. Chernesky, M. A., Delong, D. J., Mahony, J. B., And Castriciano, S., Differences in antibody responses with rapid agglutination tests for the detection of rubella antibodies, J. Clin. Microbiol. 23:772–776 (1986).

    Google Scholar 

  33. Cockburn, W. D., W.rld aspects of the epidemiology of rubella, Am. J. Dis. Child. 118: 112–122 (1969).

    Google Scholar 

  34. Committee ON Infectious Diseases, American Academy OF Pediatrics, Measles: Reassessment of the current immunization policy, Pediatrics 84: 110–112 (1989).

    Google Scholar 

  35. Cooper, L. Z., The history and medical consequences of rubella, Rev. Infect. Dis. 7:S2–S10 (1985).

    Google Scholar 

  36. Cooper, L. Z., Florman, A. L., Ziring, P. R., And Krugman, S., Loss of rubella hemagglutination inhibition antibody in congenital rubella, Am. J. Dis. Child. 122:397–403 (1971).

    Google Scholar 

  37. Cooper, L. Z., And Krugman, S., Clinical manifestations of postnatal and congenital rubella, Arch. Ophthalmol. 77:434–439 (1967).

    Google Scholar 

  38. Cradock-Watson, J. E., Ridehalgh, M. K., Anderson, M. J., Pattison, J. R., And Kangro, H. O., Outcome of asymptomatic infection with rubella virus during pregnancy, J. Hyg. 87:147–154 (1981).

    Google Scholar 

  39. Crawford, G. E., And Gremillion, D. H., Epidemic measles and rubella in Air Force recruits: Impact of immunization, J. Infect. Dis. 144:403–410 (1981).

    Google Scholar 

  40. Crener, N. E., Hagens, S. J., And Cossen, C., Comparison of the hemagglutination inhibition test and an indirect fluorescent-antibody test for detection of antibody to rubella virus in human sera, J. Clin. Microbiol. 11:746–747 (1980).

    Google Scholar 

  41. Cunningham, A. L., And Fraser, J. R. E., Persistent rubella virus infection of human synovial cells cultured in vitro, J. Infect. Dis. 151:638–645 (1985).

    Google Scholar 

  42. Dales, L. G., And Chin, J., Public health implications of rubella antibody levels in California, Am. J. Public Health 72:167–172 (1982).

    Google Scholar 

  43. Das, E. D., Lakhani, P., Kurtz, J. B., Hunter, N., Watson, B. E., Cartwright, K. A., Caul, E. O., And Roome, A. E, Congenital rubella after previous maternal immunity, Arch. Dis. Child. 65:545–546 (1990).

    Google Scholar 

  44. Dimech, W., BetrOli, A., Eckert, D., Francis, B., Hamblin, J., Kerr, T., Ryan, C., And Skurrie, I., Multicenter evaluation of five commercial rubella virus immunoglobulin G kits which report in international units per milliliter, J. Clin. Microbiol. 30: 633–641 (1992).

    Google Scholar 

  45. Dorfman, S. F., And Bowers, C. H., JR., Rubella susceptibility among prenatal and family planning clinic populations, Mt. Sinai J. Med. 52:248–252 (1985).

    Google Scholar 

  46. DoRsett, P. H., Miller, D. C., Green, K. Y., And Byrd, E I., Structure and function of the rubella virus proteins, Rev. Infect. Dis. 7:S150–5156 (1985).

    Google Scholar 

  47. Dowdle, W. R., Ferreira, W., DE Salles Gomes, L. F., King, D., KoUrany, M., Madalengoitia, J., Pearson, E., SwAnston, W. H., Tosr, H. C., And Vilches, A. M., Who collaborative study on the sero-epidemiology of rubella in Caribbean and Middle and South American populations in 1968, Bull. Who 42: 419–422 (1970).

    Google Scholar 

  48. Driscoll, S. G., Histopathology of gestational rubella, Am. J. Dis. Child. 118:49–53 (1969).

    Google Scholar 

  49. Dudgeon, J. A., Selective immunization: Protection of the individual, Rev. Infect. Dis. 7:5185-S190 (1985).

    Google Scholar 

  50. EDrroRiai., Rubella and congenital malformations, Lancet 1:316 (1944).

    Google Scholar 

  51. Enders, G., Rubella antibody titers in vaccinated and nonvaccinated women and results of vaccination during pregnancy, Rev. Infect. Dis. 7:S103–S107 (1985).

    Google Scholar 

  52. Enders, G., Calm, A., And Schaub, J., Rubella embryopathy after previous maternal rubella vaccination, Infection 12: 56–58 (1984).

    Google Scholar 

  53. Erickson, C. A., Rubella early in pregnancy causing congenital malformations of eyes and heart, J. Pediatr. 25:281–283 (1944).

    Google Scholar 

  54. Esterly, J. R., And Oppenheimer, E. H., Pathological lesions due to congenital rubella, Arch. Pathol. 87:380–388 (1969).

    Google Scholar 

  55. Evans, A. S., Cox, F., Nankervis, G., OptoN, E. M., Shope, R. E., Wells, A. V., And West, B., A health and seroepidemiological survey of a community in Barbados, Int. J. Epidemiol. 3: 167–175 (1974).

    Google Scholar 

  56. Evans, A. S., Niederman, J. C., A.D Sawyer, R. N., Prospective studies of Yale University freshmen. II. Occurrence of acute respiratory infections and rubella, J. Infect. Dis. 123: 271–278 (1971).

    Google Scholar 

  57. Ferraro, M. J., Kallas, W. M., Welch, K. P., And Lau, A. Y., Comparison of a new, rapid enzyme immunoassay with a latex agglutination test for qualitative detection of rubella antibodies, J. Clin. Microbiol. 25:1722–1724 (1987).

    Google Scholar 

  58. Fogel, A., Gerichter, C. B., Rannon, L., Bernholtz, B., And Handsher, R., Serologic studies in 11,460 pregnant women during the 1972 rubella epidemic in Israel, Am. J. Epidemiol. 103:51–59 (1976).

    Google Scholar 

  59. Fogel, A., Moshkowitz, A., Rannon, L., And Gerichter, C. B., Comparative trials of RA 27/3 and Cendehill rubella vaccines in adult and adolescent females, Am. J. Epidemiol. 93:392–398 (1971).

    Google Scholar 

  60. Forbes, J. A., Rubella, historical aspects, Am. J. Dis. Child. 118: 5–11 (1969).

    Google Scholar 

  61. Forrest, J. M., Menser, M. A., And Honeyman, M. C., Clinical rubella eleven months after vaccination, Lancet 2: 399–400 (1972).

    Google Scholar 

  62. Forrest, J. M., Slinn, R. F., Nowak, M. J., And Menser, M. A., Duration of immunity to rubella, Lancet 1: 1013 (1971).

    Google Scholar 

  63. Forsgren, M., Carlstrom, G., And Stramgert, K., Case of congenital rubella after maternal reinfection, Scand. J. Infect. Dis. 11:81–83 (1979).

    Google Scholar 

  64. Forsgren, M., And Soren, L., Subclinical rubella reinfection in vaccinated women with rubella-specific IgM response during pregnancy and transmission of virus to the fetus, J. Infect. Dis. 17:337–341 (1985).

    Google Scholar 

  65. Fraser, J. R., Cunningham, A. L., Hayes, K., Leach, R., And Lunt, R., Rubella arthritis in adults. Isolation of virus, cytology and other aspects of the synovial reaction, Clin. Exp. Rheumatol. 1:287–293 (1983).

    Google Scholar 

  66. Freestone, D. S., Prydie, J., Hamilton-Smith, S. G., And Laurence, G., Vaccination of adults with Wistar RA27/3 rubella vaccine, J. Hyg. 69: 471–477 (1971).

    Google Scholar 

  67. Frenkel, L. M., Nielsen, K., Garakian, A., Jin, R., Wolinsky, J. S., And Cherry, J. D., A search for persistent rubella virus infection in persons with chronic symptoms after rubella and rubella immunization and in patients with juvenile rheumatoid arthritis, Clin. Infect. Dis. 22: 287–294 (1996).

    Google Scholar 

  68. Frey, T. K., And Abernathy, E. S., Identification of strain-specific nucleotide sequences in the RA 27/3 rubella virus vaccine, J. Infect. Dis. 168:854–864 (1993).

    Google Scholar 

  69. Fuccillo, D. A., Steele, R. W., Hensen, S. A., Vincent, M. M., Hardy, J. B., And Bellanti, J. A., Impaired cellular immunity to rubella virus in congenital rubella, Infect. Immun. 9: 81–84 (1974).

    Google Scholar 

  70. Gale, J. L., Detels, R., Kim, K. S. W., Beasley, R. P., Chen, K. P., And Grayston, J. T., The epidemiology of rubella on Taiwan. Iii. Family studies in cities of high and low attack rates, Int. J. Epidemiol. 1:261–265 (1972).

    Google Scholar 

  71. Gale, J. L., Grayston, J. T., Beasley, R. P., Detels, R., And Kim, K. S. W., The epidemiology of rubella on Taiwan. 19681969 epidemic, Int. J. Epidemiol. 1:253–260 (1972).

    Google Scholar 

  72. Ginsberg-Fellner, F., Witt, M. E., Fedun, B., Taub, F., DoBerson, M. J., McEvoy, R. C., Cooper, L. Z., Notkins, A. L., And Rubinstein, P., Diabetes mellitus and autoimmunity in patients with the congenital rubella syndrome, Rev. Infect. Dis. 7: S170–5176 (1985).

    Google Scholar 

  73. Goldwater, P. N., Quiney, J. R., And Banatvala, J. E., Maternal rubella at St. Thomas’ Hospital: Is there a need to change British vaccination policy? Lancet 2: 1228–1230 (1978).

    Google Scholar 

  74. Goodman, A. K., Friedman, S. M., Beatrice, S. T., And Bart, S. W., Rubella in the work place: The need for employee immunization, Am. J. Public Health 77:725–726 (1987).

    Google Scholar 

  75. GoMwalk, N. E., And Ahmad, A. A., Prevalence of rubella antibodies on the African continent, Rev. Infect. Dis. 11:116–121 (1989).

    Google Scholar 

  76. Grahame, R., Armstrong, R., Simmons, N., Wilton, J. M., Dyson, M., Laurent, R., Millis, K, And Mims, C. A., Chronic arthritis associated with the presence of intrasynovial rubella virus, Ann. Rheum. Dis. 42:2–13 (1983).

    Google Scholar 

  77. Grayson, J. T., Gale, J. L., And Wattem, R. H., The epidemiology of rubella on Taiwan. I. Introduction and description of the 1957–1958 epidemic, Int. J. Epidemiol. 1:245–252 (1972).

    Google Scholar 

  78. Green, R. H., Balsamo, M. K., Giles, J. P., Krugman, S., And Mirick, G. S., Studies on the natural history and prevention of rubella, Am. J. Dis. Child. 110:348–365 (1965).

    Google Scholar 

  79. Gregg, N. M., Congenital cataract following German measles in the mother, Trans. Ophthalmol. Soc. Aust. 3:35–46 (1941).

    Google Scholar 

  80. Grillner, L., Immunity to intranasal challenge with rubella virus two years after vaccination: Comparison of three vaccines, J. Infect. Dis. 133:637–641 (1976).

    Google Scholar 

  81. Grillner, L., Forsgren, M., Barr, B., Bottiger, M., Danielsson, L., And Deverdier, C., Outcome of rubella during pregnancy with special reference to the 17th-24th weeks of gestation, Scand. J. Infect. Dis. 15: 321–325 (1983).

    Google Scholar 

  82. Habel, K., Transmission of rubella to Macacus mulatta monkeys, Public Health Rep. 57:1126–1139 (1942).

    Google Scholar 

  83. Halstead, S. B., Diwan, A. R., And Oda, A. I., Susceptibility to rubella among adolescents and adults in Hawaii, J.A.M.A. 210: 1881–1883 (1969).

    Google Scholar 

  84. Harcourt, G. C., Best, J. M., And Banatvala, J. E., Rubella-specific serum and nasopharyngeal antibodies in volunteers with naturally acquired and vaccine-induced immunity after intranasal challenge, J. Infect. Dis. 142:145–155 (1980).

    Google Scholar 

  85. Hardy, J. B. Sever, J. L. And Gilkeson, M. R., Declining antibody titers in children with congenital rubella, J. Pediatr. 75: 213–220 (1969).

    Google Scholar 

  86. Hattis, R. R, Halstead, S. B., Herrmann, K. L., And Witte, J. J., Rubella in an immunized island population, J.A.M.A. 223: 1019–1021 (1973).

    Google Scholar 

  87. Heggie, A. D., Pathogenesis of the rubella exanthem: Isolation of rubella virus from the skin, N. Engl. J. Med. 285:664–666 (1971).

    Google Scholar 

  88. Heggie, A. D., And Robbins, F. C., Natural rubella acquired after birth, clinical features and complications, Am. J. Dis. Child. 118: 12–17 (1969).

    Google Scholar 

  89. Herrmann, K. L., Rubella virus, in: Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections (E. H. Lenette And N. J. Schmidt, Eds.), pp. 725–766, American Public Health Association, Washington, DC, 1979.

    Google Scholar 

  90. Herrmann, K. L., Available rubella serologic tests, Rev. Infect. Dis. 7:S108–S112 (1985).

    Google Scholar 

  91. Herrmann, K. L., Halstead, S. B., And Wiebenga, N. H., Rubella antibody persistence after immunization, J.A.M.A. 247: 193–196 (1982).

    Google Scholar 

  92. Hess, A. F., German measles (rubella): An experimental study, Arch. Intern. Med. 13:913–916 (1914).

    Google Scholar 

  93. Hillary, I. B. And Griffiih, A. H. Persistence of rubella antibodies 15 years after subcutaneous administration of Wistar 27/3 strain live attenuated rubella virus vaccine, Vaccine 2:274276 (1984).

    Google Scholar 

  94. Hilleman, M. R., Buynak, E. V., Whitman, J. E., Weibel, R. E., And Stokes, J. Live attenuated rubella virus vaccines: Experiences with duck embryo cell preparations, Am. J. Dis. Child. 118:166–171(1969).

    Google Scholar 

  95. Hinman, A. R., Bart, K. J., Orenstein, W. A., And Preblud, S. R., Rational strategy for rubella vaccination, Lancet 1: 39–40 (1983).

    Google Scholar 

  96. Hiro, Y., And Tasaka, S., Die Roteln sind eine viruskrankheit, Monatsschr. Kinderheilkd. 76:328–332 (1938).

    Google Scholar 

  97. Hold, S., Hudgins, D., Krishnan, K. R., And Critchley, E. M. R., Diffuse myelitis associated with rubella vaccination, Br. Med. J. 2:1037–1038 (1976).

    Google Scholar 

  98. Holmes, I. H. Wark, M. C., And Andwarkburton, M. F., Is rubella an arbovirus? II. Ultrastructural morphology and development, Virology 37:15–25 (1969).

    Google Scholar 

  99. Hornstein, L. And Ben-Porath, E., Rubella antibodies in women of childbearing age during an epidemic and two years thereafter, Is. J. Med. Sci. 12:1180–1193 (1976).

    Google Scholar 

  100. Hornstein, L., Levy, U., And Fogel, A., Clinical rubella with virus transmission to the fetus in a pregnant woman considered to be immune, N. Engl. J. Med. 310:1415–1416 (1988).

    Google Scholar 

  101. Horstmann, D. M., And Liebhaber, H., Rubella, in: Serological Epidemiology (J. R. Paul And C. White, Eds.), pp. 83–97, Academic Press, New York, 1973.

    Google Scholar 

  102. Horstmann, D. M., Liebhaber, H., Lebouvier, G. L., Rosenberg, D. A., And Halstead, S. B., Rubella: Reinfection of vaccinated and naturally immune persons exposed in an epidemic, N. Engl. J. Med. 283: 771–778 (1970).

    Google Scholar 

  103. Horstmann, D. M., Riordan, J. T., Ohtawara, M., And Niederman, J. C., A natural epidemic of rubella in a closed population-Virologie and epidemiological observations, Arch. Ges. Virusforsch. 16: 438–487 (1985).

    Google Scholar 

  104. Horstmann, D. M., Schluederberg, A., Emmons, E., Evans, B. K., Randolph, M. F., And Andiman, W. A., Persistence of vaccine-induced immune responses to rubella: Comparison with natural infection, Rev. Infect. Dis. 7:S80–S85 (1985).

    Google Scholar 

  105. Inouye, S., Satoh, K., And Tajima, T., Single-serum diagnosis of rubella by combined use of the hemagglutination inhibition and passive hemagglutination tests, J. Clin. Microbiol. 23:388391 (1986).

    Google Scholar 

  106. Institute OF Medicine, Adverse Effects of Pertussis and Rubella Vaccines (C. P. HOwsoN, C. J. Howe, And H. V. Fineberg, Eds.), pp. 187–205, National Academy Press, Washington, DC, 1991.

    Google Scholar 

  107. Jackson, A. D. M., And Fisch, L., Deafness following maternal rubella. Results of a prospective investigation, Lancet 2:12411244 (1958).

    Google Scholar 

  108. Jackson, B. M., Payton, T., Horst, G., Halpin, T. J., And Mortenson, B. K., An epidemiological investigation of a rubella outbreak among the Amish of Northeastern Ohio, Public Health Rep. 108:436–439 (1993).

    Google Scholar 

  109. Jennings, S., And Thornton, L., The epidemiology of rubella in the Republic of Ireland, Communic. Dis. Rep. Rev. 3:R115–R117 (1993).

    Google Scholar 

  110. Just, M., Just, V., Berger, R., Burkardt, E, And Schilt, U., Duration of immunity after rubella vaccination: A long-term study in Switzerland, Rev. Infect. Dis. 7:S91–S94 (1985).

    Google Scholar 

  111. Kazarian, E. L., And Gager, W. E., Optic neuritis complicating measles, mumps and rubella vaccination, Am. J. Ophthamol. 86:544–547 (1978).

    Google Scholar 

  112. Kline, L. B., Margulies, S. L., And OH, S. J., Optic neuritis and myelitis following rubella vaccination, Arch. Neurol. 39:443444 (1982).

    Google Scholar 

  113. Klock, L. E., Spruance, S. L., Bailey, A., Mcquarrie, H. G., Heberstrom, R. M., Sharp, H. C., And Muth, C. B., A clinical and serological study of women exposed to rubella-virus vaccinees, Am. J. Dis. Child. 123:465–468 (1972).

    Google Scholar 

  114. KoNo, R., Hayawaka, Y., And Ishii, K., Experimental vertical transmission of rubella virus in rabbits, Lancet 1 :343–347 (1969).

    Google Scholar 

  115. Kono, R., Hirayama, M., Sugishita, C., And Miyamura, K., Epidemiology of rubella and congenital rubella infection in Japan, Rev. Infect. Dis. 7:S56–S63 (1985).

    Google Scholar 

  116. Krogh, V., Duffy, L. C., Wong, D., Rosenbrand, M., Riddlesberger, K. R., And Ogra, P. L., Postpartum immunization with rubella virus vaccine and antibody response in breast-feeding infants, J. Lab. Clin. Med. 113:695–699 (1989).

    Google Scholar 

  117. Krugman, S. (ED.), Rubella symposium, Am. J. Dis. Child. 110: 345–476 (1965).

    Google Scholar 

  118. Krugman, S. (ED.), International conference on rubella immunization, Am. J. Dis. Child. 118:2–410 (1969).

    Google Scholar 

  119. Krugman, S., And Ward, R., Rubella: Demonstration of neutralizing antibody in gamma globulin and re-evaluation of the rubella problem, N. Engl. J. Med. 259:16–19 (1958).

    Google Scholar 

  120. Krugman, S., Ward, R., Jacobs, K. G., And Lazar, M., Studies on rubella immunization-I. Demonstration of rubella without rash, J.A.M.A. 151:285–288 (1953).

    Google Scholar 

  121. Kurtz, J. B. Mortimer, P. P. Morgan-Capner, P. Shafi, M. S., And White, G. B. B., Rubella antibody measured by radial hemolysis: Characteristics and performance of a simple screening method for use in diagnostic laboratories, J. Hyg. 84:213–222 (1980).

    Google Scholar 

  122. Lasonsky, G. A., Fishaut, J. M., And Ogra, P. L., Effect of immunization against rubella on lactation products. II. Maternal-neonatal interactions, J. Infect. Dis. 145:661–666 (1982).

    Google Scholar 

  123. Lawless, M. R., Abramson, J. S., Harlan, J. E., And Kelsey, D. S., Rubella susceptibility in sixth graders: Effectiveness of current immunization practice, Pediatrics 65: 1086–1089 (1980).

    Google Scholar 

  124. Lee, P. R., Barnett, A. E, Scholer, J. F., Bryner, S., And Clark, W. H., Rubella arthritis: A study of twenty cases, Calif. Med. 93:125–128 (1960).

    Google Scholar 

  125. Lee, S. H., Ewert, D. P., Frederick, P. D., And Mascola, L., Resurgence of congenital rubella syndrome in the 1990s, J.A.M.A. 267:2616–2620 (1992).

    Google Scholar 

  126. Lehane, D. E., Newberg, N. R., And Beam, W. E., JR., Evaluation of rubella herd immunity during an epidemic, J.A.M.A. 213: 2236–2239 (1970).

    Google Scholar 

  127. Lennette, E. H., Schmidt, N. J., And Magoffin, R. L., The hemagglutination-inhibition test for rubella: A comparison of its sensitivity to that of neutralization, complement fixation, and fluorescent antibody tests for diagnosis of infection and determination of immunity status, J. Immunol. 99:785–793 (1967).

    Google Scholar 

  128. Levine, J. B., Berkowitz, C. D., And ST. Geme, J. W., Rubella virus reinfection during pregnancy leading to late-onset congenital rubella syndrome, J. Pediatr. 100: 589–591 (1982).

    Google Scholar 

  129. Liebhaber, H., Measurement of rubella antibody by hemagglutination inhibition. I. Variables affecting rubella hemagglutination, J. Immunol. 104:818–825 (1970).

    Google Scholar 

  130. Liebhaber, H., Measurement of rubella antibody by hemagglutination inhibition. II. Characteristics of an improved Hai test employing a new method for the removal of non-immunoglobulin HA inhibitors from serum, J. Immunol. 104:826–834 (1970).

    Google Scholar 

  131. Lindegren, M. L., Fehrs, L. J., Hadler, S. C., And Hinman, A. R., Update: Rubella and congenital rubella syndrome, 19801990, Epidemiol. Rev. 13:341–348 (1991).

    Google Scholar 

  132. Lundstrom, R., Rubella during pregnancy-A follow-up study of children born after an epidemic of rubella in Sweden, 1951, with additional investigations on prophylaxis and treatment of maternal rubella, Acta. Paediatr. 51(Suppl. 133):1–110 (1962).

    Google Scholar 

  133. Manson, M. M., Logan, W. P. D., And Loy, R. M., Rubella and other virus infections during pregnancy, in: Reports on Public Health and Medical Subjects, No. 101, Ministry of Health, H.M.S.O., London, 1960.

    Google Scholar 

  134. Manton, W. G., Some accounts of rash liable to be mistaken for scarlitina, Med. Trans. R. Coll. Physicians 5:149 (1815).

    Google Scholar 

  135. Marks, J. S., Serdula, M. K., Halsey, N. A., Gunaratne, M. V., Craven, R. B., Murphy, K. A., Kobayashi, G. Y., And Wiebenga, N. H., Saturday night fever: A common-source outbreak of rubella among adults in Hawaii, Am. J. Epidemiol. 114:574–583 (1981).

    Google Scholar 

  136. Martin, S. M., Congenital defects and rubella, Br. Med. J. 1:855 (1945).

    Google Scholar 

  137. Mayo, D. R., Sirpenski, S. P., And Markowski, M. A., Micro-titer latex agglutination-quantitative and qualitative equivalent to hemagglutination inhibition for detection of rubella antibody, Diagn. Microbiol. Infect. Dis. 5:55–59 (1986).

    Google Scholar 

  138. Meegan, J. M., Evans, B. K., And Horstmann, D. M., Comparison of the latex agglutination test with the hemagglutination test, enzyme-linked immunosorbent assay, and neutralization test for detection of antibodies to rubella virus, J. Clin. Microbiol. 16: 644–649 (1982).

    Google Scholar 

  139. Meegan, J. M., Evans, B. K., And Horstmann, D. M., Use of enzyme immunoassays and the latex agglutination test to measure the temporal appearance of immunoglobulin G and M antibodies after natural infection or immunization with rubella virus, J. Clin. Microbiol. 18:745–748 (1983).

    Google Scholar 

  140. Mellinger, A. K., Cragan, J. D., Atkinson, W. L., Williams, W. W., Kleger, B., Kimber, R. A., Tavris, D., High incidence of congenital rubella syndrome after a rubella outbreak, Pediatr. Infect. Dis. J. 14:573–578 (1995).

    Google Scholar 

  141. Menser, M. A., Forrest, J. M., Bransby, R. D., And Collins, E., Rubella vaccination in Australia: Experiences with the RA27/3 rubella vaccine and results of a double-blind trial in schoolgirls, Med. J. Aust. 2: 85–88 (1978).

    Google Scholar 

  142. Menser, M. A., Forrest, J. M., Honeyman, M. C., And Burgress, J. A., Diabetes, Hla-antigens and congenital rubella, Lancet 2: 1508–1509 (1974).

    Google Scholar 

  143. Menser, M. A., Hudson, J. R., Murphy, A. M., And Upfold, L. J., Epidemiology of congenital rubella and results of rubella vaccination in Australia, Rev. Infect. Dis. 1:S37–S41 (1985).

    Google Scholar 

  144. Menser, M. A., Slinn, R. F., Dods, L., Hertzberg, R., And Harley, J. D., Congenital rubella in a mother and son, Aust. Paediatr. J. 4:200–202 (1968).

    Google Scholar 

  145. Mettler, N. E., Peterelli, R I, And Casals, J., Absence of cross reactions between rubella virus and arbovirus, Virology 36: 503–504 (1968).

    Google Scholar 

  146. Meurman, O. H., Viljanen, M. K., And Granfors, K., Solid-phase radioimmunoassay of rubella virus immunoglobulin M antibodies: Comparison with sucrose density gradient centrifugation test., J. Clin. Microbiol. 5:257–262 (1977).

    Google Scholar 

  147. Meyer, H. M., Parkman, P. D., Hobbins, T. E., Larson, H. E., Davis, W. S., Simsarian, J. P., And Hopps, H. E., Attenuated rubella viruses: Laboratory and clinical characteristics, Am. J. Dis. Child. 118:155–165 (1969).

    Google Scholar 

  148. Meyer, H. M., Parkman, P. D., And Panos, T. C., Attenuated rubella virus. II. Production of an experimental live-virus vaccine and clinical trial, N. Engl. J. Med. 275:575–580 (1966).

    Google Scholar 

  149. Miller, E., Rubella in the United Kingdom, Epidemiol. Infect. 107:21–42 (1991).

    Google Scholar 

  150. Miller, E., Cradock-Watson, J. E., And Pollack, T. M., Consequences of confirmed rubella at successive stages of pregnancy, Lancet 1: 871–874 (1982).

    Google Scholar 

  151. Miller, E, Waight, P. A., Vurdien, J. E., Jones, G., Tookey, P. A., And Peckham, C. S., Rubella surveillance to December 1992: Second joint report from the Phls and National Congenital Rubella Surveillance Programme, Communic. Dis. Rep. Rev. 3(3):R35–R40 (1993).

    Google Scholar 

  152. a. Mims, C. A., Stokes, A., And Grahame, R., Synthesis of antibodies, including antiviral antibodies, in the knee joints of patients with arthritis, Ann. Rheum. Dis. 44:734–737 (1985).

    Google Scholar 

  153. Modlin, J. E., Herrmann, K. L., Brandling-Bennett, A. D., Eddins, D. L., And Hayden, G. E, Risk of congenital abnormality after inadvertent rubella vaccination of pregnant women, N. Engl. J. Med. 294: 972–974 (1976).

    Google Scholar 

  154. Morgan-Capner, P., Miller, E., Vurdien, J. E., And Ramsay, M. E. B., Outcome of pregnancy after maternal reinfection with rubella, Communic. Dis. Rep. Rev. 1:R57–R59 (1991).

    Google Scholar 

  155. Morton-Kute, L., Rubella vaccine and facial paresthesias, Ann. Intern. Med. 102:563 (1985).

    Google Scholar 

  156. Murphy, E A., Halonen, P. A., And Harrison, A. K., Electron microscopy of the development of rubella virus in Bhk-21 cells, J. Virol. 2:1223–1227 (1968).

    Google Scholar 

  157. Naeye, R. L., And Blanc, W., Pathogenesis of congenital rubella, J.A.M.A. 194:1277–1283 (1965).

    Google Scholar 

  158. National Communicable Disease Center, Rubella surveillance, Report No. 1, June 1969.

    Google Scholar 

  159. Ogra, R L., Kerr-Grant, D., Umana, G., Dzierba, J., And Weintraub, D., Antibody response in serum and nasopharynx after infections with rubella virus, N. Engl. J. Med. 285: 1333–1339 (1971).

    Google Scholar 

  160. Orenstein, W. A., Bart, K. J., Hinman, A. R., Preblud, S. R., Greaves, W. L., Doster, S. W., Stetler, H. C., And Sirotkin, B., The opportunity and obligation to eliminate rubella from the United States, J.A.M.A. 251:1988–1994 (1984).

    Google Scholar 

  161. Orenstein, W. A., Herrmann, K. L., Holmgreen, P., Bernier, R., Bart, K. J., Eddins, D. L., And Fiumara, N. J., Prevalence of rubella antibodies in Massachusetts school children, Am. J. Epidemiol. 124:290–298 (1986).

    Google Scholar 

  162. Orenstein, W. A., Heseltine, R N. R., Legagnoux, S. J., And Portnoy, B., Rubella vaccine and susceptible hospital employees. Poor physician participation, J.A.M.A. 245:711–713 (1981).

    Google Scholar 

  163. O’Shea, S., Best, J. M., Banatvala, J. E., Marshall, W. C., And Dudgeon, J. A., Rubella vaccination persistence of antibodies for up to 16 years, Br. Med. J. 285:253–255 (1982).

    Google Scholar 

  164. O’Shea, S., Best, J. M., And Banatvala, J. E., Viremia, virus excretion, and antibody responses after challenge in volunteers with low levels of antibody to rubella virus, J. Infect. Dis. 148: 639–647 (1983).

    Google Scholar 

  165. O’Shea, S., Best, J. M., Banatvala, J. E., Marshall, W. C., And Dudgeon, J. A., Persistence of rubella antibody 8–18 years after vaccination, Br. Med. J. 288:1043 (1984).

    Google Scholar 

  166. Parkman, R D., Buescher, E. L., And Artenstein, M. S., Recovery of rubella virus from army recruits, Proc. Soc. Exp. Biol. Med. 111:225–230 (1962).

    Google Scholar 

  167. Parkman, P. D.,Buescher, E. L., Artenstein, M. S., Mccown, J. M., Mundon, E K., And Druzd, A. D., Studies of rubella. I. Properties of the virus, J. Immunol. 93:595–607 (1964).

    Google Scholar 

  168. Partridge, J. W., Flewett, T. H., And Whitehead, J. E., Congenital rubella affecting an infant whose mother had rubella antibodies before conception, Br. Med. J. 282:187–188 (1981).

    Google Scholar 

  169. Peckham, C. S., Clinical and laboratory study of children exposed in utero to maternal rubella at successive stages of pregnancy, Arch. Dis. Child 47:571–577 (1972).

    Google Scholar 

  170. Peckham, C., Congenital rubella in the United Kingdom before 1970: The prevaccine era, Rev. Infect. Dis. 7:S11–S16 (1985).

    Google Scholar 

  171. Peltola, H., And Heinonen, O. P., Frequency of true adverse reactions to measles-mumps-rubella vaccine: A double-blind placebo-controlled trial in twins, Lancet 1: 939–942 (1986).

    Google Scholar 

  172. a. Peltola, H. And Heinonen, O. P., Valle, M., Pavnio, M., Virtanen, M., Karanko, V., And Cantell, K., The elimination of indigenous measles, mumps, and rubella from Finland by a 12-year, two-dose vaccination program, N. Engl. J. Med. 331: 1397–1402 (1994).

    Google Scholar 

  173. Petterson, R. E, Oker-Blom, C., Kalkkinen, N., Kallio, A., Ulmanen, I., Kaariainen, L., Partanen, R, And Vaheri, A., Molecular and antigenic characteristics and synthesis of rubella virus structural proteins, Rev. Infect. Dis. 7: S140 - S149 (1985).

    Google Scholar 

  174. Plotkin, S. A., Attenuation of RA27/3 rubella virus in WI-38 human diploid cells, Am. J. Dis. Child. 118:178–185 (1969).

    Google Scholar 

  175. Plotkin, S. A., And Buser, E, History of RA27/3 rubella vaccine, Rev. Infect. Dis. 7:S77–S88 (1985).

    Google Scholar 

  176. Plotkin, S. A., Farquhar, J. D., And Ogra, R L., Immunologic properties of RA27/3 rubella virus vaccine, J.A.M.A. 225:585590 (1973).

    Google Scholar 

  177. Polk, B. F., White, J. A., Degirolami, P C., And Modlin, J. F., An outbreak of rubella among hospital personnel, N. Engl. J. Med. 303: 541–545 (1980).

    Google Scholar 

  178. Polk, B. F., Modlin, J. E, White, J. A., And Degirolami, P. C., A controlled comparison of joint reactions among women receiving one of two rubella vaccines, Am. J. Epidemiol. 115:19–25 (1982).

    Google Scholar 

  179. Preblud, S. R., Serdula, M. K., Frank, J. A., JR., Brandlingbennett, A. D., And Hinman, A. R., Rubella vaccination in the United States: A ten-year review, Epidemiol. Rev. 2: 171–194 (1980).

    CAS  Google Scholar 

  180. Prinzie, A., Huygelen, C., Gold, J., Farquhar, J., And Mckee, J., Experimental live attenuated rubella virus vaccine: Clinical evaluation of Cendehill strain, Am. J. Dis. Child. 118:172–177 (1969).

    Google Scholar 

  181. RAwLS, W. E., Melnick, J. L., Bradstreet, C. M. P., Bailey, M., Ferris, A. A., Tiehmann, N., Nagler, F. P., Furesz, J., Koxo, R., Ohtawara, M., Halonen, P., Stewart, J., Ryan, J. M., Strauss, J., Zdrazilek, J., Leerhop, J., Von Magnus, H., Sohier, R., And Ferreira, W., Who collaborative study on the seroepidemiology of rubella, Bull. Who 37: 79–88 (1967).

    Google Scholar 

  182. Ray, P., Black, S., Shinefeld, H., Dillon, A., Schwalbe, J., Holmes, S., Chen, R., Williams, W., And Cochi, S., Retrospective cohort evaluation of chronic rubella vaccine arthropathy, 34th Interscience Conference on Antimicrocial Agents and Chemotherapy, American Society for Microbiology, Orlando, Florida, October 4–7, 1994 (Abstract).

    Google Scholar 

  183. Reese, A B, Congenital cataract and other anomalies following German measles in the mother, Am. J. Ophthamol. 27: 483–487 (1944).

    Google Scholar 

  184. a. Report of an international meeting on rubella vaccines and vaccination, 9 August 1993, Glasgow, United Kingdom, J. Infect. Dis. 170:507–509 (1994).

    Google Scholar 

  185. Richardson, D., Rubella immunisation status of year 8 females in the Midwest and Gascoyne, Western Australia, Communic. Dis. Intell. 12:308–310 (1993).

    Google Scholar 

  186. Robinson, R. G., Dudenhoeffer, F. E., Holroyd, H. J., Baker, L. R., Bernstein, D. I., And Cherry, J. D., Rubella immunity in older children, teenagers, and young adults: A comparison of immunity in those previously immunized and those unimmunized, J. Pediatr. 101:188–191 (1982).

    Google Scholar 

  187. Rones, B., The relationship of German measles during pregnancy to congenital ocular defects, Med. Ann. D. C. 13:285–287 (1944).

    Google Scholar 

  188. Ross, R., Harvey, D. R., And Hurley, R., Re-infection and congenital rubella syndrome, Practitioner 236: 246–251 (1992).

    Google Scholar 

  189. Rowlands, D. E, And Freestone, D. S., Vaccination against rubella of susceptible schoolgirls in Reading, J. Hyg. 69:579–586 (1971).

    Google Scholar 

  190. Sander, J., And Niehaus, C., Screening for rubella IgG and IgM using an Elisa test applied to dried blood on filter paper, J. Pediatr. 106:457–461 (1985).

    Google Scholar 

  191. Saule, H., Enders, G., Zeller, J., And Bernsau, U., Congenital rubella infection after previous immunity of the mother, Eur. J. Pediatr. 147:195–196 (1988).

    Google Scholar 

  192. Schaffner, W., Fleet, W. E, Kilroy, A. W., Lefkowitz, L. B., Herrmann, K. L., Thompson, J., And Karzon, D. T., Polyneuropathy following rubella immunization. A follow-up study and review of the problem, Am. J. Dis. Child. 127: 684–688 (1974).

    Google Scholar 

  193. Schatzmayr, H. G., Aspects of rubella infection in Brazil, Rev. Infect Dis. 7:553-S55 (1985).

    Google Scholar 

  194. Schiff, G. M., Young, B. C., Stefanovic, G. M., Stamler, E. E, Knowlton, D. R., Grundy, B. J., And Dorsett, P. H., Challenge with rubella virus after loss of detectable vaccine-induced antibody, Rev. Infect. Dis. 7:S157–5163 (1985).

    Google Scholar 

  195. Schluederberg, A., Horstmann, D. M., Andiman, W. A., And Randolph, M. E, Neutralizing and hemagglutinationinhibiting antibodies to rubella virus as indicators of protective immunity in vaccinees and naturally immune individuals, J. Infect. Dis. 138:877–883 (1978).

    Google Scholar 

  196. Schoub, B. D., Blackburn, N. K., O’CoNnell, K., Kaplan, A., B., And Adno, J., Symptomatic rubella reinfection in early pregnancy and subsequent delivery of an infected but minimally involved infant, S. Aft Med. J. 78: 484–485 (1990).

    Google Scholar 

  197. Sciium, T. R., Nelson, D. B., Duma, M. A., And Sedmak, G. V., Increasing rubella seronegativity despite a compulsory school law, Am. J. Public Health 80:66–69 (1990).

    Google Scholar 

  198. ScoTT, H. D., And Byrne, E. B., Exposure of susceptible pregnant women to rubella vaccinees. Serologic findings during the Rhode Island immunization campaign, J.A.M.A. 215:609–612 (1971).

    Google Scholar 

  199. Sepppala, M., And Vaheri, A., Natural rubella infection of the female genital tract, Lancet 1: 46–47 (1974).

    Google Scholar 

  200. Serdula, M. K., Halstead, S. B., Wiebenga, N. H., And Herrmann, K. L., Serological response to rubella revaccination, J.A.M.A. 251:1974–1977 (1984).

    Google Scholar 

  201. Sever, J. L., The epidemiology of rubella, Arch. Ophthalmol. 77:427–429 (1967).

    Google Scholar 

  202. Sever, J. L., Fuccillo, D. A., Gilkeson, M. R., Ley, A., And Traub, R., Changing susceptibility to rubella, Obstet. Gynecol. 32:365–369 (1968).

    Google Scholar 

  203. Sever, J. L., Schiff, G. M., And Huebner, R. J., Frequency of rubella antibody among pregnant women and other human and animal populations, Obstet. Gynecol. 23:153–159 (1964).

    Google Scholar 

  204. Sever, J. L., South, M. A., And Shaver, K. A., Delayed manifestations of congenital rubella, Rev. Infect. Dis. 7:S164–169 (1985).

    Google Scholar 

  205. Sheppard, S., Smithells, R. W., Dickson, A., And Holzel, H., Rubella vaccination and pregnancy: Preliminary report of a national survey, Br. Med. J. (Clin. Res.) 292:727 (1986).

    Google Scholar 

  206. Siegel, M., And Greenberg, M., Fetal death, malformation and prematurity after maternal rubella: Results of prospective study, 1949–1958, N. Engl. J. Med. 262:389–393 (1960).

    Google Scholar 

  207. Sigurjonsson, J., Rubella and congenital deafness, Am. J. Sci. 240:712–720 (1961).

    Google Scholar 

  208. SandMoxs, M. J., Congenital rubella: An immunological paradox ? Lancet 2: 1275–1278 (1968).

    Google Scholar 

  209. Skendzel, L. E, Carski, T. R., Herrmann, K. L., Kiefer, D. J., Nakamura, R. M., Nutter, C. D., And Schaefer, L. E., Evaluation and performance criteria for multiple component test products intended for the detection and quantitation of rubella IgG antibody, Natl. Comm. Clin. Lab. Stand. 12:1–24 (1992).

    Google Scholar 

  210. Skendzel, L. P., Wilcox, K. R., And Edson, D., Evaluation of assays for the detection of antibodies to rubella. A report based on data from the College of American Pathologists surveys 1982, Am. J. Clin. Pathol. 80(Suppl.):594–598 (1983).

    Google Scholar 

  211. Slater, P. E., Ben-Zvi, T., Fogel, A., Ehrenfeld, M., And Ever-Hadani, S., Absence of an association between rubella vaccination and arthritis in underimmune postpartum women, Vaccine 13: 1529–1532 (1995).

    Google Scholar 

  212. Soothhill, J. E, Hayes, K., And Dudgeon, J. D., The immunoglobulins in congenital rubella, Lancet 1: 1385–1388 (1966).

    Google Scholar 

  213. South, M. A., Montgomery, J. K., And Rawls, W. D., Immune deficiency in rubella and other viral infections, Birth Defects 11: 234–238 (1975).

    Google Scholar 

  214. Spruance, S. L., And Smith, C. B., Joint complications associated with derivatives of Hpv-77 rubella vaccine, Am. J. Dis. Child. 122:105–111 (1971).

    Google Scholar 

  215. Stanley, F. J., Sim, M., Wilson, G., And Worthington, S., The decline in congenital rubella syndrome in Western Australia: An impact of the the school girl vaccination program?, Am. J. Public Health 76:35–37 (1986).

    Google Scholar 

  216. Stehr-Green, P. A., Cochi, S. L., Preblud, S. R., Orenstein, W. A., Evidence against increasing rubella seronegativity among adolescent girls, Am. J. Public Health 80: 88 (1990).

    Google Scholar 

  217. Storch, G. A., And Myers, N., Latex-agglutination test for rubella antibody: Validity of positive results assessed by response to immunization and comparison with other tests, J. Infect Dis. 149:459–464 (1984).

    Google Scholar 

  218. Strassburg, M. A., Imagawa, D. T., Fannin, S. L. Turner, J. A., Chow, A. W., Murray, R. A., And Cherry, J. D., Rubella outbreak among hospital employees, Obstet. Gynecol. 57:283288 (1981).

    Google Scholar 

  219. Swan, C., Tostevin, A. L., And Black, G. H. B., Final observations on congenital defects in infants following infectious diseases during pregnancy, with special reference to rubella, Med. J. Aust. 2:889–908 (1946).

    Google Scholar 

  220. Swan, C., TosTEvmN, A. L., Moore, B., Mayo, H., And Black, G. H. B., Congenital defects in infants following infectious diseases during pregnancy. With special reference to the relationship between German measles and cataract, deaf-mutism, heart disease and microcephaly, and to the period of pregnancy in which the occurrence of rubella is followed by congenital abnormalities, Med. J. Aust. 11: 201–210 (1943).

    Google Scholar 

  221. Swartz, T. A., An extensive rubella epidemic in Israel, 1972: Selected epidemiologic characteristics, Am. J. Epidemiol. 103:60–66 (1976).

    Google Scholar 

  222. Swartz, T. A., Hornstein, L. And Epstein, I., Epidemiology of rubella and congenital rubella infection in Israel, a country with a selective immunization program, Rev. Infect. Dis. 7:S42–S46 (1985).

    Google Scholar 

  223. Tingle, A. J., Chantler, J. K., Pot, K. H., Paty, D. W., And Ford, D. K., Postpartum rubella immunization: Association with development of prolonged arthritis, neurological sequelae, and chronic rubella viremia, J. Infect. Dis. 52:606–612 (1985).

    Google Scholar 

  224. Tingle, A. J., Allen, M., Petty, R. E., Kettyls, G. D., And Chantler, J. K., Rubella-associated arthritis. I. Comparative study of joint manifestations associated with natural rubella infection gnd RA 27/3 rubella immunisation, Ann. Rheum. Dis. 45: 110–114 (1986).

    Google Scholar 

  225. Tobin, J. O., Sheppard, S., Smithells, R. W., Milton, A., Noah, N., And Reid, D., Rubella in the United Kingdom, 1970–1983, Rev. Infect. Dis. 7:S47–S52 (1985).

    Google Scholar 

  226. ToNdury, Y. G., And Smith, D. W., Fetal rubella pathology, J. Pediatr. 68:867–879 (1966).

    Google Scholar 

  227. Ueda, K., Nonaka, S., Yoshikawa, H., Sasaki, K., Segawa, H., Fujii, H., Tasaki, H., Shin, H., Tokugawa, K., And Sato, T., Seroepidemiologic studies of rubella in Fukuoka in Southern Japan during 1965–1981: Rubella epidemic pattern, endemicity and immunity gap, Int. J. Epidemiol. 12: 450–454 (1983).

    Google Scholar 

  228. Ueda, K., Sasaki, F., Tokugawa, K., Segawa, K. And Fujii, H. The 1976–1977 rubella epidemic in Fukuoka city in Southern Japan: Epidemiology and incidences of complications among 80,000 persons who were school children at 28 primary schools and their family members, Biken J. 27:161–168 (1984).

    Google Scholar 

  229. Ukkonen, P, And Von Bonsdorff, C.-K., Rubella immunity and morbidity: Effects of vaccination in Finland, Scand. J. Infect. Dis. 20:255–259 (1988).

    Google Scholar 

  230. Vaananen, R Haiva, V.-M., Koskela, P. And Meurman, O., Comparison of a simple latex agglutination test with hemolysisin-gel, hemagglutination inhibition, and radioimmunoassay for detection of rubella virus antibodies, J. Clin. Microbiol. 21:793795 (1985).

    Google Scholar 

  231. Valensin, P. E., Rossolini, G. M., Cusi, M. G., Zanchi, A., Cellesi, C., And Rossolini, A., Specific antibody patterns over a two-year period after rubella immunization with RA 27/3 live attenuated vaccine, Vaccine 5:289–294 (1987).

    Google Scholar 

  232. Veale, H. History of an epidemic of Rotheln, with observations on its pathology, Edinburgh Med. J. 12:404–414 (1866).

    Google Scholar 

  233. Vogt, R. L., And Clark, S. W., Premarital rubella vaccination program, Am. J. Public Health 75:1088–1089 (1985).

    Google Scholar 

  234. Voller, A. D., Bidwell, D., And Bartlett, A., Enzyme linked immunosorbent assay, in: Manual of Clinical Immunity, 2nd ed. (N. R. Rose And H. Friedman, Ens.), pp. 359–371, American Society for Microbiology, Washington, DC, 1980.

    Google Scholar 

  235. Waxham, M. N., And Wolinsky, J. S., Rubella virus and its effect on the central nervous system, Neurol. Clin. 2:367–385 (1984).

    Google Scholar 

  236. Waxham, M. N., And Wolinsky, J. S., A model of the structural organization of rubella virions, Rev. Infect. Dis. 7:S133–S139 (1985).

    Google Scholar 

  237. Weibel, R. E., Stokes, J., JR., Buynak, E. B., And Hilleman, M. R., Influence of age on clinical responses to Hpv77 duck rubella vaccine, J.A.M.A. 222: 805–807 (1972).

    Google Scholar 

  238. Weller, T. H., And Neva, F. A., Propagation in tissue culture of cytopathic agents from patients with rubella-like illness, Proc. Soc. Exp. Biol. Med. 11:215–225 (1962).

    Google Scholar 

  239. Wesselhoeft, C., Rubella (German measles), N. Engl. J. Med. 236:943–950, 978–988 (1947).

    Google Scholar 

  240. Wielaard, F., Denissen, A., Van Elleswuk-Van Der Berg, J. And Van Gemert, G., Clinical validation of an antibody capture anti-rubella IgM Elisa, J. Virol. Methods 10:349–354 (1985).

    Google Scholar 

  241. Wild, N. J., Sheppard, S., Smithells, R. W. Holzel, H. And Jones, G., Onset and severity of hearing loss due to congenital rubella infection, Arch. Dis. Child. 64:1280–1283 (1989).

    Google Scholar 

  242. Wilkins, J. Leedom, J. M., Portnoy, B. And Salvatore, M. A., Reinfection with rubella virus despite live vaccine induced immunity. Trials of Hpv-77 and Hpv-80 live rubella virus vaccines and subsequent artificial and natural challenge studies, Am. J. Dis. Child. 118:275–294 (1969).

    Google Scholar 

  243. Wilkins, J. Leedom, J. M., Salvatore, M. A., And Portnoy, B. Clinical rubella with arthritis resulting from reinfection, Ann. Intern. Med. 77:930–932 (1972).

    Google Scholar 

  244. WI1lh, J. J. Karchmer, A. W., Case, G., Herrmann, K. L., Kassanoff, I. And Neill, J. S., Epidemiology of rubella, Am. J. Dis. Child. 118:107–111 (1969).

    Google Scholar 

  245. Wolf, J. E., Eisen, J. E., And Fraimow, H. S., Symptomatic rubella reinfection in an immune contact of a rubella vaccine recipient, So. Med. J. 86:91–93 (1993).

    Google Scholar 

  246. Wolinsky, J. S., Berg, B. O., And Maitland, C. J., Progressive rubella panencephalitis, Arch. Neurol. 33:722–723 (1976).

    Google Scholar 

  247. World Health Organization, Lab/82. 1. Evaluation of candidate international reference methods for the rubella hemagglu- tination-inhibition tests. Report of a collaborative study, 1982.

    Google Scholar 

  248. Zhang, T., Mauracher, C. A., Mitchell, L. A, And Tingle, A. J., Detection of rubella virus-specific immunoglobulin G (IgG), IgM, and IgA antibodies by immunoblot assays, J. Clin. Microbiol. 30:824–830 (1992).

    Google Scholar 

  249. Zolti, M., Zion, B. R., Bider, D., Mashiach, S., And Fogel, A., Rubella-specific IgM in reinfection and risk to the fetus, Gynecol. Obstet. Invest. 30:184–185 (1990).

    Google Scholar 

  250. Suggested Reading

    Google Scholar 

  251. Cherry, J. D., Rubella, in: Textbook of Infectious Diseases 3rd ed. (J. D. Cherry And R. D. Feigin, Eds.), pp. 1792–1817, W. B. Saunders, Philadelphia, 1992.

    Google Scholar 

  252. Gershon, A. A., Rubella virus (German measles), in: Principles and Practices of Infectious Diseases 3rd ed. (G. L. Mandfli, R. G. Douglas, JR., And J. R. Bennett, Eds.), pp. 1242–1247, Churchill Livingstone, New York, 1990. International Symposium on the Prevention of Congenital Rubella Infection, Rev. Infect. Dis. 7(Suppl. 1):S1—S215 (1985).

    Google Scholar 

  253. Maldonaldo, Y. A., Rubella virus, in: Pediatric Infectious Diseases (S. S. Long, L. K. Pickering, And C. G. Prober, Eds.), pp. 1228–1237, Churchill Livingstone, New York, 1997.

    Google Scholar 

  254. Plotkin, S. A., Rubella vaccine, in: Vaccines (S. A. Plotkin And E. A. Mortimer, Eds.), pp. 303–336, W. B. Saunders, Philadelphia, 1994. Preblud, S. R., And Alford, C. A., Rubella, in: Infectious Diseases of the Fetus and Newborn Infant 3rd ed. (J. S. Remington And J. O. Klein, Eds.), pp. 196–240, W. B. Saunders, Philadelphia, 1983. Wolinsky, J. S., Rubella, in: Virology 2nd ed. (B. N. Fields, D. M. Knipe, R. M. Chanock, M. S. Hirsch, J. L. Melnick, T. P. Monath, And B. Roizman, Eds.), pp. 815–838, Raven Press, New York, 1990.

    Google Scholar 

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Holmes, S.J., Orenstein, W.A. (1997). Rubella. In: Evans, A.S., Kaslow, R.A. (eds) Viral Infections of Humans. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0036-4_27

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