Abstract
Thymomas are epithelial tumors that have a strong correlation to autoimmune disease. A classification that correlates with prognosis has been proposed. We classified 79 thymoma specimens and identified the CK immunophenotypes of these tumors.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Rosai J, Levine GD. Tumors of the thymus. In: Atlas of tumor pathology, 2nd series, fascicle 13. Armed Forces Institute of Pathology, 1976. Washington.
Pescarmona E, Rendina EA, Venuta F, Ricci C, Ruco LP, Baroni CD. The prognostic implication of thymoma histologic subtyping: A study of 80 consecutive cases. Am J Clin Pathol. 1990:93(2): 190–195.
Lewis JE, Wick MR, Scheithauer BW et al: Thymoma: A clinicopathological review. Cancer. 1987; 60:2727–2743.
Kornstein MJ. Pathology of the thymus and mediastinum. Vol 33 in the series Major Problems in Pathology. WB Saunders, Philadelphia 1995.
Kendall MD: The morphology of perivascular spaces in the thymus. Thymus. 1989; 13:157–164.
Müller-Hermelink HK, Marino M, Palestro G, Schumacher U, Kirchner T. Immunohistological evidence of cortical and medullary differentiation in thymoma. Virchows Arch A Pathol Anat Histopathol. 1985;408:143–161.
Marino M, Müller-Hermelink HK: Thymoma and thymic carcinoma. Relation of thymoma epithelial cells to the cortical and medullary differentiation of the thymus. Virchows Arch A Pathol Anat Histopathol. 1985; 407:119–49.
Kirchner T, Müller-Hermelink HK: New approaches to the diagnosis of thymic epithelial tumors. Prog Surg Pathol. 1989; 10:167–189.
Quintanilla-Martinez L, Wilkins EW Jr, Choi N, Efird J, Hug E, Harris NL: Thymoma. Histologic subclassification is an independent prognostic factor. Cancer. 1994; 74:606–617.
Kirchner T, Schalke B, Buchwald J, Ritter M, Marx A, Müller-Hermelink HK. Well differentiated thymic carcinoma: an organotypical low-grade carcinoma with relationship to cortical thymoma. Am J Surg Pathol. 1992:16; 1153–1169.
Fukai L, Masaoka A, Hashimoto T, Yamakawa Y, Mizuno T, Tanamura O: Cytokeratins in normal thymus and thymic epithelial tumors. Cancer. 1993; 71:99–105.
Moll R: Molecular diversity of cytokeratins: significance for cell and tumor differentiation. Acta Histochem Suppl. 1991; 41:117–127.
Moll R, Schiller DL, Franke WW. Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression pattern. J Cell Biol. 1990; 111:567–580.
Moll R, Löwe A, Laufer J, Franke WW: Cytokeratin 20 in human carcinomas: a new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol. 1992; 140:427–447.
Colic M, Jovanovic S, Mitrovic S, Dujic A: Immunohistochemical identification of six cytokeratin-defined subsets of the rat thymic epithelial cells. Thymus. 1989; 13:175–85.
Colic M, Jovanovic S, Vasiljevski M, Dujic A: Ontogeny of thymic epithelium defined by monoclonal anticytokeratin antibodies. Dev Comp Immunol. 1990; 1:67–75.
Shezen E, Okon E, Ben Hur H, Abramsky O: Cytokeratin expression in human thymus: Immunohistochemical mapping. Cell Tissue Res. 1995; 279:221–231.
Kuratani S, Bockman DE: Impaired development of the thymic primordium after neural crest ablation. Anat Rec. 1990; 228:185–190.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer Science+Business Media New York
About this chapter
Cite this chapter
Enoksson, J.P., Albertsson, M., Cervin, A., Friström, K., Johansson, L. (1997). Cytokeratin (CK) Profile in Thymomas. In: Marx, A., Müller-Hermelink, H.K. (eds) Epithelial Tumors of the Thymus. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0033-3_10
Download citation
DOI: https://doi.org/10.1007/978-1-4899-0033-3_10
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4899-0035-7
Online ISBN: 978-1-4899-0033-3
eBook Packages: Springer Book Archive