Divided Visual Field Studies in Schizophrenia

  • Anthony S. David


Ever since Hippocrates, physicians have been trying to locate the origin of madness somewhere in the brain. It was not until 1844, that Wigan (1844) suggested that insanity might be due to the failure of the two cerebral hemispheres to work in harmony. Such a thesis remained ignored until the 1960’s when a generation of psychologists produced an impressive body of research illuminating the role of the corpus callosum (CC) in integrating brain function. They did this by studying individuals who had undergone surgical division of the CC (see for example Gazzaniga, et al. (1965)), or had become ‘disconnected’ by lesions from other sources (Geschwind, 1965). The function of this broad band of more than 200,000,000 myelinated fibres was inferred from the effects of its transection which led to speculation regarding the unity of conscious experience, the unconscious and the mind-body problem (see Sperry, 1968). Psychiatry tends to lag behind psychology by about a decade and so it was not until the early 1970’s that questions were raised as to whether this new knowledge might be relevant to the understanding of abnormal mental phenomena (Lishman, 1971; Galin, 1974).


Schizophrenic Patient Hemisphere Asymmetry Verbal Task Cerebral Laterality Psychiatric Control 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Alpert, M. Rubenstein, & Kesselman, M. (1976). Asymmetry of information processing in hallucinators and nonhallucinators. Journal of Nervous and Mental Disease, 162 258–265.Google Scholar
  2. American Psychiatric Association (1980). Diagnostic and Statistical Manual of Mental Disorder (DSM-III) (3rd Edit.). Washington DC: APA. Bashore, T.R. (1981). Vocal and manual reaction time estimates of inter- hemispheric transmission time. Psychological Bulletin, 89 352–368. Beaton, A. (1985). Left Side/Right Side. A Review of Laterality Research. London: Bratsford Academic & Educational.Google Scholar
  3. Beaumont, J.G. (1982). Divided Visual Field Studies of Cerebral Organisation. London: Academic Press.Google Scholar
  4. Beaumont, J.G. & Dimond, S. (1973). Brain disconnection and schizophrenia. British Journal of Psychiatry, 123 661–662.Google Scholar
  5. Bleuler, P.E. (1911). Dementia Praecox and the Group of Schizophrenias (translated, 1950). New York: International University Press. Bradshaw, J.L. & Nettleton, N.C. (1981). The nature of hemispheric specialization in man. Behavioural and Brain Sciences, 4 51–91.Google Scholar
  6. Braff, D.L. & Saccuzzo, D.P. (1982). Effect of antipsychotic medication on speed of information processing in schizophrenic patients. American Journal of Psychiatry, 139 661–662.Google Scholar
  7. Chapman, L.J. & Chapman, J.P. (1973). Problems in the measurement of cognitive deficit. Psychological Bulletin, 79 380–385.Google Scholar
  8. Chapman, L.J. & Chapman, J.P. (1977). Selection of subjects in studies of schizophrenic cognition. Journal of Abnormal Psychology, 86 10–15.Google Scholar
  9. Clooney, J.L. & Murray, D.J. (1977), same-different judgements in paranoid and non-paranoid schizophrenic patients: a laterality study. Journal of Abnormal Psychology, 86 655–658.Google Scholar
  10. Colbourn, C.J. (1982). Divided visual field studies of psychiatric patients. in: J.G. Beaumont (ed.), Divided Visual Field Studies of Cerebral Organisation London: Academic Press.Google Scholar
  11. Colbourn, C.J. & Lishman, W.A. (1979). Lateralization of function and psychotic illness: a left hemisphere deficit? in: J.H. Gruzelier & P. Flor-Henry (eds.), Hemisphere Asymmetries of Function in Psychopathology Amersterdam: Elsevier/North Holland Biomedical Press.Google Scholar
  12. Connolly, J.F., Gruzelier, J.H., Kleinman, K.M. & Hirsch, S.R. (1979). Lateralised abnormalities in hemisphere-specific tachistoscopic task in psychiatric patients and controls. in: J.H. Gruzelier & P. Flor-Henry (eds.), Hemisphere Asymmetries of Function in Psychopathology Amsterdam: Elsevier/North Holland Biomedical Press.Google Scholar
  13. Connolly, J.F., Gruzelier, J.H. & Manchanda, R. (1983). Electrocortical and functional asymmetries in schizophrenia. in: P. Flor-Henry & J. Gruzelier (eds), Laterality and Psychopathology Amersterdam: Elsevier/North Holland Biomedical Press.Google Scholar
  14. Cutting, J.C. (1985). The Psychology of Schizophrenia. London: Churchill Livingstone.Google Scholar
  15. David, A.S. (1987). Tachistoscopic tests of colour naming and matching in schizophrenia: evidence for posterior callosum dysfunction? Psychological Medicine, 17 621–630.Google Scholar
  16. David, A.S., Jeste, D.V., Folstein, M.F. & Folstein, S.E. (1987). Voluntary movement dysfunction in Huntington’s disease and tardive dyskinesia. Acta Neurologica Scandinavica, 75 130–139.Google Scholar
  17. Eaton, E.M. (1979). Hemisphere-related visual information processing in acute schizophrenia. Before and after neuroleptic treatment. in: J.H. Gruzelier & P. Flor-Henry (eds.), Hemisphere Asymmetries of Function in Psychopathology Amsterdam: Elsevier/North Holland Biomedical Press.Google Scholar
  18. Eaton, E.M., Busk, J., Maloney, M.P., Sloane, R.B., Whipple, K. & White, K. (1979). Hemisphere dysfunction in schizophrenia: assessment by visual perception taks. Psychiatric Research, 1 325–332.Google Scholar
  19. Galin, D. (1974). Implications for psychiatry of left and right cerebral specialization. Archives of General Psychiatry, 31 572–583.Google Scholar
  20. Gazzaniga, M.S., Bogen, J.E. & Sperry, R.W. (1965). Observations on visual perception after disconnexion of the cerebral hemispheres in man. Brain, 88 16–36.Google Scholar
  21. George, L. & Neufeld, R.W.J. (1987). Attentional resources and hemispheric functional asymmetry in schizophrenia. British Journal of Clinical Psychology, 26 35–45.Google Scholar
  22. Geschwind, N. (1965). Disconnexion syndromes in animals and man. Brain 88, 237–294 and 585–644.Google Scholar
  23. Geschwind, N. & Fusillo, M. (1966). Color naming defects in association with alexia. Archives of Neurology, 15 137–146.Google Scholar
  24. Goldstein, G. (1986). The neuropsychology of schizophrenia. in: I.G. Grant & K.M. Adams (eds.), Neuropsychological Assessment in Neuro-psychiatric Disorders New York: Oxford University Press.Google Scholar
  25. Gruzelier, J.H. (1981). Cerebral laterality and psychopathology: fact and fiction. Psychological Medicine, 11 219–227.Google Scholar
  26. Gruzelier, J.H. (1984). Hemispheric imbalances in schizophrenia. International Journal of Psychophysiology, 1 227–240.Google Scholar
  27. Gur, R.E. (1978). Left hemisphere dysfunction and left hemisphere over-activation in schizophrenia. Journal of Abnormal Psychology, 87 226–238.Google Scholar
  28. Gur, R.E. (1979). Cognitive concomitants of hemisphere dysfunction in schizophrenia. Archives of General Psychiatry, 36 269–274.Google Scholar
  29. Hammond, N.V. & Gruzelier, J.H. (1978). Laterality, attention and rate effects in the auditory temporal discrimination of chronic schizophrenics: the effect of treatment with chlorpromazine. Quarterly Journal of Experimental Psychology, 30 91–103.Google Scholar
  30. Hillsberg, B. (1979). A comparison of visual discrimination performance of the dominant and nondominant hemispheres in schizophrenia. in: J.H. Gruzelier & P. Flor-Henry (eds.), Hemisphere Asymmetries of Function in Psychopathology Amsterdam: Elsevier/North Holland Biomedical press.Google Scholar
  31. Holzman, P.S. (1987). Recent studies of psychophysiology in schizophrenia. Schizophrenia Bulletin, 13 49–75.Google Scholar
  32. Johnson, O. & Crockett, D. (1982). Changes in perceptual asymmetries with clinical improvement of depression. Journal of Abnormal Psychology 91, 45–54.Google Scholar
  33. Liddle, P.F. (1987). The symptoms of chronic schizophrenia: a reexamination of the positive-negative dichotomy. British Journal of Psychiatry, 151 145–151.Google Scholar
  34. Liederman, J. & Meehan, P. (1986). When is between-hemisphere division of labour advantageous? Neuropsychologia, 24 863–874.Google Scholar
  35. Lishman, W.A. (1971). Emotion, consciousness and will after brain bisection in man. Cortex, 7 181–192.Google Scholar
  36. Magaro, P., Abrams, L. & Cantrell, P. (1981). The Maine Scale of paranoid and non-paranoid schizophrenia: reliability and validity. Journal of Consultative Clinical Psychology, 49 438–447.Google Scholar
  37. Magaro, P.A. & Page, J. (1983). Brain disconnection, schizophrenia and paranoia. Journal of Nervous and Mental Disease, 171 133–140.Google Scholar
  38. Merriam, A.E. & Gardener, E.B. (1987). Corpus callosum function in schizophrenia: a neuropsychological assessment of interhemispheric information processing. Neuropsychologia, 25 185–193.Google Scholar
  39. Moscovitch, M. (1986). Afferent and efferent models of visual perceptual asymmetries: theoretical and empirical implications. Neuropsychologia, 24 91–114.Google Scholar
  40. Nelson, H.E. & O’Connell, A. (1978). Dementia: the estimation of premorbid intelligence levels using the new adult reading test. Cortex 14, 234–244.Google Scholar
  41. Neuchterlein, K.H. & Dawson, M.E. (1984). Information processing and attentional functioning in the developmental course of schizophrenic disorders. Schizophrenia Bulletin, 10 160–203.Google Scholar
  42. Newlin, D.B., Carpenter, B. & Golden, C.J. (1981). Hemispheric asymmetries in schizophrenia. Biological Psychiatry, 16 561–582.Google Scholar
  43. Pic’l, A.K., Magaro, P.A. & Wade, E.A. (1979). Hemispheric functioning in paranoid and non-paranoid schizophrenia. Biological Psychiatry, 14 891–903.Google Scholar
  44. Robertson, G. & Taylor, P.J. (1987). Laterality and psychosis: neuro- psychological evidence. British Medical Bulletin, 43 634–650.Google Scholar
  45. Robertson, R. & Bigelow, L.B. (1972). Quantitative brain measurements in chronic schizophrenia. British Journal of Psychiatry, 121 259–264.Google Scholar
  46. Ross-Kossak, P. & Turkewitz, G. (1984). Relationship between changes in hemispheric advantage during familiarization to faces and proficiency in facial recognition. Neuropsychologia, 22 471–477.Google Scholar
  47. Schweitzer, L. (1982). Evidence of right hemisphere dysfunction in schizophrenic patients with left hemisphere overactivation. Biological Psychiatry, 17 655–673.Google Scholar
  48. Schwartz, B.D., Winstead, D.K. & Walker, W.G. (1984). A corpus callosal deficit in sequential analysis by schizophrenics. Biological Psychiatry, 19 1667–1676.Google Scholar
  49. Sergent, J. (1983). The role of the input in visual hemispheric asymmetries. Psychological Bulletin, 93 481–512.Google Scholar
  50. Shelton, E.J. & R.G. Knight (1984). Inter-hemispheric transmission times in schizophrenics. British Journal of Clinical Psychology, 24 227–228.Google Scholar
  51. Shenton, M.E., Solovay, M.R. & Holzman, P. (1987). Comparative studies of thought disorder II: schizoaffective disorder. Archives of General Psychiatry, 44 21–30.Google Scholar
  52. Sperry, R.W. (1968). Hemisphere deconnection and unity in conscious awareness. American Psychologist, 23 723–733.Google Scholar
  53. Spitzer, R.L. & Endicott, J. & Robins, E. (1975). Research Diagnostic Criteria. New York: New York State Psychiatric Institute.Google Scholar
  54. Walker, E. & McGuire, M. (1982). Intra and inter-hemispheric information processing in Schizophrenia. Psychological Bulletin, 92 701–725.Google Scholar
  55. Wexler, B.E. (1986). Alterations in cerebral laterality during acute psychotic illness. British Journal of Psychiatry, 149 202–209.Google Scholar
  56. Wigan, A.L. (1844). The Duality of the Mind. London: Longman.Google Scholar
  57. Wing, J.K. & Wing, L. (1982). Handbook of Psychiatry Vol 3. Psychoses of Uncertain Origin. Cambridge: Cambridge University Press.Google Scholar
  58. Young, A.W. (1982). Methodological and theoretical bases. in: J.G. Beaumont (ed.), Divided Visual Field Studies of Cerebral Organisation London: Academic Press.Google Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Anthony S. David

There are no affiliations available

Personalised recommendations