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Checkpoints and Functional Stages in DC Maturation

  • Claudia Winzler
  • Patrizia Rovere
  • Valerie S. Zimmermann
  • Jean Davoust
  • Maria Rescigno
  • Stefania Citterio
  • Paola Ricciardi-Castagnoli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 417)

Abstract

A major breakthrough in our understanding of the regulation of immune responses has been the discovery of a number of integrated functions of the dendritic cells (DC) in the immune system. To better define the checkpoints and the functional stages in DC development one should be able to mimic and control DC maturation in vitro, from the initial irreversible commitment towards final stages of maturation.

Keywords

Dendritic Cell Dendritic Cell Maturation Immature Dendritic Cell Mature Dendritic Cell Antigen Uptake 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Claudia Winzler
    • 1
  • Patrizia Rovere
    • 2
  • Valerie S. Zimmermann
    • 2
  • Jean Davoust
    • 2
  • Maria Rescigno
    • 1
  • Stefania Citterio
    • 1
  • Paola Ricciardi-Castagnoli
    • 1
  1. 1.CNR Centre of Cellular and Molecular PharmacologyMilanItaly
  2. 2.Centre d’Immunologie INSERM-CNRS de Marseille LuminyMarseilleFrance

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