Routes of Administration for Polar Compounds of Moderate Molecular Weight with Particular Reference to Analogues of Somatostatin

  • Colin McMartin
  • Gill Peters
Part of the NATO ASI Series book series (NSSA, volume 125)


Somatostatin (SS) is a 14-amino acid peptide with a cystine bridge forming a 12-amino acid ring. SS suppresses the release of many peptide hormones (eg: insulin; glucagon; growth hormone). Interest has centred on its potential use in acromegaly (growth hormone suppression) and diabetes (glucagon suppression). Because of its multiple actions it has been considered necessary to search for analogues with more specific properties.


Sodium Cromoglycate Horse Radish Peroxidase Depot Effect Nasal Administration Nasal Absorption 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Colin McMartin
    • 1
  • Gill Peters
    • 1
  1. 1.Horsham Research CentreCIBA-GEIGY PharmaceuticalsHorsham, West SussexUK

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