Controlled Delivery of Nafarelin, An Agonistic Analogue of LHRH, From Microspheres of Poly (D, L Lactic-Co-Glycolic) Acid
The present rapid expansion of activity in development of peptide and protein drug compounds has provided a major thrust for development of novel technology for their delivery. These compounds have typically very low oral bioavailability (although this elusive goal is sufficiently attractive for it to remain an active area of exploration).
KeywordsPLGA Microsphere LHRH Agonist Male Rhesus Monkey LHRH Analogue Diffusional Release
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