Pathology of Cytomegalovirus Infection
The history and practice of the pathology of CMV infection has until recently been dominated by cytomegaly, the large giant cells with type A intranuclear inclusion (Cowdry, 1934). The classical pathology of C.I.D. is well described in standard texts, particularly Seifert and Oehme (1957), and is not repeated here in detail. In acute neonatal and adult infections, CMV has been detected by morphological means in a wide variety of organs, including the salivary glands, lung, liver, pancreas, kidney, eye, ear, placenta, alimentary tract, heart, ovaries, anterior pituitary gland, adrenal gland, thyroid, brain, and skin (Seifert and Ohme, 1957; Rosen and Hajdu, 1971; Stagno et al., 1977c).
KeywordsSalivary Gland Intranuclear Inclusion Hemorrhagic Cystitis Congenital Infection Microglial Nodule
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