Pathology of Cytomegalovirus Infection

  • Monto Ho


The history and practice of the pathology of CMV infection has until recently been dominated by cytomegaly, the large giant cells with type A intranuclear inclusion (Cowdry, 1934). The classical pathology of C.I.D. is well described in standard texts, particularly Seifert and Oehme (1957), and is not repeated here in detail. In acute neonatal and adult infections, CMV has been detected by morphological means in a wide variety of organs, including the salivary glands, lung, liver, pancreas, kidney, eye, ear, placenta, alimentary tract, heart, ovaries, anterior pituitary gland, adrenal gland, thyroid, brain, and skin (Seifert and Ohme, 1957; Rosen and Hajdu, 1971; Stagno et al., 1977c).


Salivary Gland Intranuclear Inclusion Hemorrhagic Cystitis Congenital Infection Microglial Nodule 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Monto Ho
    • 1
    • 2
  1. 1.Graduate School of Public Health and School of MedicineUniversity of PittsburghPittsburghUSA
  2. 2.Presbyterian-University HospitalPittsburghUSA

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