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Methodology for Simulation of Metabolic Pathways and Calculation of Control Coefficients

  • Pedro Mendes
  • João Moniz Barreto
  • Ana Vaz Gomes
  • Ana Ponces Freire
Chapter
Part of the NATO ASI Series book series (NSSA, volume 190)

Abstract

The main advantage of metabolic control theory is that it is not necessary to consider enzyme kinetic mechanisms for an experimental analysis of real biochemical systems. Control coefficients can be directly determined by measuring the system response to a small perturbation of some external parameter. This can be accomplished without any knowledge of the kinetic model; the only requirement is that the system response may be measured.

Keywords

Rate Equation Microscopic Model External Parameter Macroscopic Model Elasticity Coefficient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • Pedro Mendes
    • 1
  • João Moniz Barreto
    • 1
  • Ana Vaz Gomes
    • 1
  • Ana Ponces Freire
    • 1
  1. 1.Centro de Estudos de Bioquímica e Fisiologia AnimalInstituto Rocha CabralLisboaPortugal

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