Control of Breathing by Neuropeptides

  • Marie-Pierre Morin-Surun
  • Jean Champagnat
  • Arthur Foutz
  • Monique Denavit-Saubié


Respiratory rhythm is partly generated by the periodic actions of classical neurotransmitters which act at the synapse level between different types of respiratory neurons. Periodic glutamate-like excitations (Denavit-Saubié et al., 1978) have been described as well as GABA- and glycine-like inhibitions (Champagnat et al., 1982). A new type of neuroactive substance, neuropeptides, are present in the respiratory networks and are involved in the control of the respiratory rhythm. We have been interested in those which are released in the nucleus tractus solitarii (NTS): cholecystokinin, enkephalins, substance P, neurotensin (Morin-Surun et al., 1983, 1984a,b,c, 1986; Hurlé et al., 1985a).


Opioid Peptide Nucleus Tractus Solitarii Respiratory Rhythm Respiratory Neuron Neuroactive Substance 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Marie-Pierre Morin-Surun
    • 1
  • Jean Champagnat
    • 1
  • Arthur Foutz
    • 1
  • Monique Denavit-Saubié
    • 1
  1. 1.Laboratoire de Physiologie NerveuseC.N.R.S.Gif-sur-YvetteFrance

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