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Serial Submental Stimulation during Sleep in Patients with Obstructive Sleep Apnea

  • Wataru Hida
  • Shinichi Okabe
  • Satoru Ebihara
  • Tatsuya Chonan
  • Yoshihiro Kikuchi
  • Tamotsu Takishima

Abstract

We previously reported that submental electrical stimulation may be an effective treatment for obstructive sleep apnea (Miki et al., 1989a, Hida et al., 1991). The mechanism of relief of apneic episodes during submental stimulation may be the contraction of genioglossus and/or geniohyoid muscles, which would open the upper airway by pulling the tongue forward (Miki et al, 1989b, Gottfried et al., 1983). However, the effects of submental stimulation during consecutive nights on apneic episodes in patients with obstructive sleep apnea (OSA) have not been studied. In the present study in order to assess whether submental stimulation is necessary for treatment every night, we examined the effects of submental stimulation for a serial four or five sleep nights on apneic episodes and changes in apneic episodes on stimulation-off nights after the stimulation nights using a portable submental stimulator which we have developed.

Keywords

Obstructive Sleep Apnea Airway Resistance Ventilatory Response Desaturation Index Sleep Night 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Dekker, E., Pelser, H.E., and Groen, J., 1957 Conditioning as a cause of asthmatic attack, J Psychosom Res. 2:97.PubMedCrossRefGoogle Scholar
  2. Dudley, D.L., and Pitts-Porch A.R., 1980, Psychophysiologic aspects of respiratory control, Clin Chest Med. 1:131.PubMedGoogle Scholar
  3. Gallego, J., and Perruchet, P., 1991 Classical conditioning of ventilatory responses in humans, J Appl Physiol. 70:676.PubMedGoogle Scholar
  4. Gottfried, S.B., Strohl, K.P., Van de Graaff, W., Fouke, J.M., DiMarco, A.F., 1983, Effects of phrenic stimulation on upper airway resistance in anesthetized dogs, J Appl Physiol. 55:419.PubMedGoogle Scholar
  5. Guilleminault, C., Cummiskey, J., and Dement, W.C., 1980, Sleep apnea syndrome; recent advances, in “Advances in Internal Medicine, Vol. 26,” Stollerman, G.H., ed., Year Book Medical Publishers, Chicago.Google Scholar
  6. Hida, H., Miki, H., Kikuchi, Y., Chonan, T., and Takishima, T., 1991, Treatment of obstructive sleep apnea with airflow demand-type submental stimulator, in “Control of Breathing and Dyspnea,” T. Takishima and N.S. Cherniack, ed., Pergamon Press, Oxford.Google Scholar
  7. Miki, H., Hida, W., Chonan, T., Kikuchi, Y., and Takishima, T., 1989a, Effects of submental electrical stimulation during sleep on upper airway patency in patients with obstructive sleep apnea, Am. Rev. Respir. Dis. 140:1285.PubMedCrossRefGoogle Scholar
  8. Miki, H., Hida, W., Kikuchi, Y., Chonan, T., Satoh, M., Iwase, N., and Takishima, T., 1992, Effects of pharyngeal lubrication on the opening of obstructive upper airway, J Appl Physiol. In press.Google Scholar
  9. Miki, H., Hida, W., Shindoh, C, Kikuchi, Y., Chonan, T., Taguchi, O., Inoue, H., and Takishima, T., 1989b, Effects of electrical stimulation of the genioglossus on upper airway resistance in anesthetized dogs, Am. Rev. Respir. Dis. 140:1279.PubMedCrossRefGoogle Scholar
  10. Tobin, MJ., Perez, W., Guenther, S.M., D’Alonzo, G., and Dantzker, D.R., 1986 Breathing pattern and metabolic behavior during anticipation of exercise, J Appl Physiol. 60:1306.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Wataru Hida
    • 1
  • Shinichi Okabe
    • 1
  • Satoru Ebihara
    • 1
  • Tatsuya Chonan
    • 1
  • Yoshihiro Kikuchi
    • 1
  • Tamotsu Takishima
    • 1
  1. 1.First Department of Internal MedicineTohoku University School of MedicineSendaiJapan

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