Does Sustained Hypoxia Have Biphasic Effects on the Sensation of Dyspnea?
The effect of sustained hypoxia on respiration is reported to be biphasic and comprised of an initial stimulatory phase mediated by peripheral chemoreceptors and a following depressive phase caused by central mechanisms (Neubauer, 1990). However, it is not clear how sustained hypoxia affects respiratory sensations. In this study we wished to ascertain whether sustained hypoxia has a biphasic effects on the sensation of dyspnea as well as on ventilation.
KeywordsMinute Ventilation Hypoxic Exposure Biphasic Effect Peripheral Chemoreceptor Mouth Pressure
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