Laryngeal Afferent Activity and its Role in the Control of Breathing

  • Franca B. Sant’Ambrogio
  • James W. Anderson
  • Giuseppe Sant’Ambrogio

Abstract

The afferent activity emerging from the larynx travels through the superior laryngeal nerve and the recurrent laryngeal nerve. Recording whole nerve activity from the internal branch of the superior laryngeal nerve, the pathway which carries most of the laryngeal afferent information, reveals a clear respiratory-related activity. This respiratory modulation is related to changes in transmural pressure, activity of laryngeal muscles, pulling on the larynx due to the respiratory movements of the trachea and changes in temperature.

Keywords

Furosemide Capsaicin Cough Gluconate 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    G. Sant’Ambrogio, O.P. Mathew, J.T. Fisher, and F.B. Sant’Ambrogio, Laryngeal receptors responding to transmural pressure, airflow and local muscle activity, Respir.Physiol. 54:317 (1983).CrossRefGoogle Scholar
  2. 2.
    G. Sant’Ambrogio, J.W. Anderson, F.B. Sant’Ambrogio, and O.P. Mathew, Response of laryngeal receptors to water solutions of different osmolality and ionic composition, Respir.Med. 85:57 (1991).CrossRefGoogle Scholar
  3. 3.
    G. Sant’Ambrogio, O.P. Mathew, and F.B. Sant’Ambrogio, Laryngeal cold receptors, Respir.Physiol. 59:35 (1985).CrossRefGoogle Scholar
  4. 4.
    G. Sant’Ambrogio, F. Brambilla-Sant’Ambrogio, and O.P. Mathew, Effect of cold air on laryngeal mcchanorcceptors in the dog, Respir.PhysioL 64:45 (1986).CrossRefGoogle Scholar
  5. 5.
    J.W. Anderson, F.B. Sant’Ambrogio, O.P. Mathew, and G. Sant’Ambrogio, Water-responsive laryngeal receptors in the dog are not specialized endings, Respir.PhysioL 79:33 (1990).PubMedCrossRefGoogle Scholar
  6. 6.
    F.B. Sant’Ambrogio, O.P. Mathew, W.D. Clark, and G. Sant’Ambrogio, Laryngeal influences on breathing pattern and posterior cricoarytenoid muscle activity, J.Appl.Physiol. 58:1298 (1985).Google Scholar
  7. 7.
    J.W. Anderson, F.B. Sant’Ambrogio, and G. Sant’Ambrogio, Changes in osmolality modify the pressure response of laryngeal receptors, FASEB J. 5:A1119 (1991).Google Scholar
  8. 8.
    W.L. Eschenbacker, H.A. Boushey, and D. Sheppard, Alteration in osmolality of inhaled aerosols cause bronchoconstriction and cough, but absence of a permeant anion causes cough alone, Am.Rev.Respir.Dis. 129:211 (1984).Google Scholar
  9. 9.
    P.G. Ventresca, G.M. Nichol, P.J. Barnes, and K.F. Chung, Inhaled furosemide inhibits cough induced by low chloride content solutions but not by capsaicin, Am.Rev.Respir.Dis. 142:143 (1990).PubMedCrossRefGoogle Scholar
  10. 10.
    F.B. Sant’Ambrogio, G. Sant’Ambrogio, and J.W. Anderson, Furosemide modifies the response of laryngeal “irritant” receptors to low-chloride solutions, FASEB J. 5:A1119 (1991).Google Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Franca B. Sant’Ambrogio
    • 1
  • James W. Anderson
    • 1
  • Giuseppe Sant’Ambrogio
    • 1
  1. 1.Department of Physiology and BiophysicsThe University of Texas Medical Branch at GalvestonGalvestonUSA

Personalised recommendations