Solitary Pulmonary Nodule

  • Jeffrey E. Weiland
Part of the Contemporary Internal Medicine book series (COIM, volume 3)


A 49-year-old female bank executive presented to Ohio State University Hospitals for a routine physical. She had not seen a physician since her last child was born (age 38) but she was due for a promotion which required a physical examination. She denied any physical complaints. She had a forty pack-year history of smoking. Her past medical history was only remarkable for three pregnancies resulting in healthy term deliveries. She was born and raised in a small town in Ohio but had lived in an urban setting for the past 20 years.


Pulmonary Nodule Plain Film Bronchogenic Carcinoma Solitary Pulmonary Nodule Transbronchial Needle Aspiration 


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  1. 1.
    Lillington GA: Systematic diagnostic approach to pulmonary nodules, in Fishman AP (ed): Pulmonary Diseases and Disorder. New York, McGraw-Hill Book Co. Inc., 1988, pp 1945–1954.Google Scholar
  2. 2.
    Doll R, Peto R: Cigarette smoking and bronchial carcinoma: Dose and time relationships among regular smokers and lifelong non-smokers. J Epidemiol Community Health. 1978;32:303–313.PubMedCrossRefGoogle Scholar
  3. 3.
    Doll R, Peto R: Mortality in relation to smoking: 20 year’s observations on male British doctors. Br Med J 1976;2:1525–1536.PubMedCrossRefGoogle Scholar
  4. 4.
    Smoking and Health. A report of the Surgeon General. Washington DC, US Department of Health, Education and Welfare, Publ. No. (PHS) 79-50066, 1979.Google Scholar
  5. 5.
    Mizuno T, Masaoka A, Ichimura H, et al: Comparison of actual survivorship after treatment with survivorship predicted by actual tumor-volume doubling time from tumor diameter at first observation. Cancer. 1984;53:2716–20.PubMedCrossRefGoogle Scholar
  6. 6.
    Siegelman SS, Zerhouni EA, Leo FP, et al: CT of the solitary pulmonary nodule. Am J Roentgenol. 1980;135:1–3.CrossRefGoogle Scholar
  7. 7.
    Proto AU, Thomas SR: Pulmonary nodules studied by computed tomography. Radiology. 1985;156:149.PubMedGoogle Scholar
  8. 8.
    Zerhouni EA, Spivey JF, Morgan RH, et al: Factors influencing quantitative CT measurements of solitary pulmonary nodules. J Comput Assist Tomogr. 1982;6:1075–1087.PubMedCrossRefGoogle Scholar
  9. 9.
    Zerhouni EA, Boukadoum M, Siddiky MA: A standard phantom for quantitative CT analysis of pulmonary nodules. Radiology. 1983;149:767.PubMedGoogle Scholar
  10. 10.
    Zerhouni EA, Stitik FP, Siegelman SS, et al: CT of the pulmonary nodule: A cooperative study. Radiology. 1986;160:319–327.PubMedGoogle Scholar
  11. 11.
    Khouri NF, Stitik FP, Erozan YS, et al: Transthoracic needle aspiration biopsy of benign and malignant lung lesions. Am J Roentgenol. 1985;144:281.CrossRefGoogle Scholar
  12. 12.
    Shure D, Fedullo PJ: Transbronchial needle aspiration of peripheral masses. Am Rev Respir Dis 1983;128:1090–1092.PubMedGoogle Scholar
  13. 13.
    Khouri NF, Meziane MA, Zerhouni EA, et al: The solitary pulmonary nodule. Assessment, diagnosis, and management. Chest. 1987;91:128–133.Google Scholar
  14. 14.
    Hooper RG, Beechler CR, Johnson MC: Radioisotope scanning in the initial stage of bronchogenic carcinoma. Am Rev Respir Dis. 1978;118:279.PubMedGoogle Scholar
  15. 15.
    Ramsdell JW, Peters RM, Taylor AT, et al: Multiorgan scans for staging lung cancer. Correlation with clinical evaluation. J Thorac Cardiovasc Surg. 1977;73:653.Google Scholar
  16. 16.
    Turner P, Haggith JW: Preoperative radionuclide scanning in bronchogenic carcinoma. Br J Dis Chest. 1981;75:291.PubMedCrossRefGoogle Scholar
  17. 17.
    Baron RL, Levitt RG, Sagal SS: Computed tomography in the preoperative evaluation in bronchogenic carcinoma. Radiology. 1982;145:727.PubMedGoogle Scholar
  18. 18.
    Underwood GH Jr, Hooper RG, Axelbaum SP, et al: Computed tomographic scanning of the thorax in the staging of bronchogenic carcinoma. N Engl J Med. 1979;300:777–778.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Jeffrey E. Weiland

There are no affiliations available

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