Rapidly Progressive Rosacea in an Adult Male With Flushing Attacks, Pruritus, and “Freckles”

  • Jonathan K. Wilkin
Part of the Contemporary Internal Medicine book series (COIM, volume 3)


A 58-year-old man had a 12-month history of facial flushing and a progressively deteriorating facial “complexion.” He was a salesman who traveled frequently by automobile, and he had flushing attacks when traveling on hot days in his non-air-conditioned vehicle. Over the past year, the flushing had become more severe and was associated with a burning sensation of the face and copious rhinorrhea. He also described abundant “freckles” on his chest and back which appeared approximately one year before this presentation. Over the past few months he had noted an increase in pruritus and urticaria localized to these “freckles,” especially after ingestion of alcoholic beverages, after hot showers, and following aspirin ingestion. He described having one episode of explosive diarrhea weekly, almost always after ingestion of 3–5 cans of beer. Persistent rhinitis, epigastric discomfort, and watery, burning eyes had been problems over recent months. The pruritus and substernal burning sensation occurred during and shortly after the flushing reactions. There had been no localized skeletal pain, fainting spells, or bleeding problems.


Mast Cell Carcinoid Tumor Carcinoid Syndrome Systemic Mastocytosis Meibomian Gland 


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© Springer Science+Business Media New York 1991

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  • Jonathan K. Wilkin

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