Abstract
Our neurobiological studies of the lateral amygdala (LA) and perirhinal cortex (PR) suggest a novel and testable hypothesis regarding encoding the time interval between the conditioned stimulus (CS) and unconditioned stimulus (US) in fear conditioning. In such conditioning, the interval between the onset of the CS and the onset of the US can be several seconds or longer. Here we outline our working hypothesis in qualitative terms, showing how the functional anatomy and neurophysiology furnish a platform for encoding the CS-US interval by mapping time onto space and then relying upon a conventional Hebbian learning rule in which the modifications require temporal contiguity of pre- and postsynaptic activity.
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© 1997 Springer Science+Business Media New York
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Faulkner, B., Tieu, K.H., Brown, T.H. (1997). Mechanism for Temporal Encoding in Fear Conditioning. In: Bower, J.M. (eds) Computational Neuroscience. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9800-5_99
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DOI: https://doi.org/10.1007/978-1-4757-9800-5_99
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