Self-Organizing Circuits of Model Neurons

  • L. F. Abbott
  • O. Jensen


Activity can affect the growth patterns of neurons as well as modifying their membrane and synaptic conductances. Most models of activity-dependent plasticity have concentrated on one of these aspects, most commonly synaptic plasticity. We construct and study a model in which all three forms of plasticity are present. Starting from random initial conditions, an array of these model cells can develop spontaneously into a highly coupled circuit displaying a complex pattern of activity. Although all the model cells are described by identical equations, they differentiate within these circuits and individually show a variety of intrinsic characteristics.


Model Neuron Intracellular Calcium Concentration Maximal Conductance Equilibrate Network Synaptic Conductance 


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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • L. F. Abbott
    • 1
  • O. Jensen
    • 1
  1. 1.Volen Center for Complex SystemsBrandeis UniversityWalthamUSA

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