Pyramidal Cell Response to Patterns of Synaptic Input Believed to Underlie Gamma Oscillations

  • Alexander D. Protopapas
  • James M. Bower


The fast oscillations induced in the piriform cortex in response to olfactory stimuli were first recorded some 50 years ago [1]. Since then, 30–80 Hz oscillations (also called gamma) have been found in many other cortical areas as well [4]. The ubiquity of stimulus-induced oscillatory activity in the brain suggests that the neural activity that underlies such oscillations might be critical to neural computation [2]. The question then becomes: How does one elucidate the neural activity that gives rise to these oscillations?


Synaptic Input Piriform Cortex Gamma Oscillation Theta Cycle Single Gamma 
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  1. [1]
    E. D. Adrian. Olfactory reactions in the brain of the hedgehog. J. Physiol. (London), 100: 459–473, 1942.Google Scholar
  2. [2]
    J. M. Bower. Reverse engineering the nervous system: An in vivo, in vitro, and in computo approach to understanding the mammalian olfactory system. In S. F. Zometzer, J. L. Davis, and C. Lau, editors, An introduction to neural and electronic networks, pages 3–28. Academic Press, New York, N. Y., second edition, 1995.Google Scholar
  3. [3]
    J. M. Bower and D. Beeman. The Book of GENESIS.. Exploring Realistic Neural Models with the GEneral NEural Simulation System. Springer-Verlag, New York, 1995.Google Scholar
  4. [4]
    C. M. Gray. Synchronous oscillations in neuronal systems: mechanisms and functions. J. Comput. Neurosci., 1: 11–38, 1994.PubMedCrossRefGoogle Scholar
  5. [5]
    K. L. Ketchum and L. B. Haberly. Membrane currents evoked by afferent fiber stimulation in rat piriform cortex. I. Current source-density analysis. J. Neurophysiol., 69 (l): 248–260, 1993.PubMedGoogle Scholar
  6. [6]
    K. L. Ketchum and L. B. Haberly. Membrane currents evoked by afferent fiber stimulation in rat piriform cortex. Il. Analysis with a system model. J. Neurophysiol., 69 (1): 261–281, 1993.PubMedGoogle Scholar
  7. [7]
    K. L. Ketchum and L. B. Haberly. Synaptic events that generate fast oscillations in piriform cortex. J. Neurosci., 13 (9): 3980–3985, 1993.PubMedGoogle Scholar
  8. [8]
    J. McCollum, J. Larson, T. Otto, F. Schottler, R. Granger, and G. Lynch. Short-latency single unit processing in olfactory cortex. J. Cogn. Neurosci., 3 (3): 293–299, 1991.CrossRefGoogle Scholar
  9. [9]
    U Mitzdorf. Current source-density method and application in cat cerebral cortex: Investigation of evoked potentials and EEG phenomena. Physiol. Rev, 65 (1): 37–100, 1985.PubMedGoogle Scholar
  10. [10]
    M. Wilson and J. M. Bower. Cortical oscillations and temporal interactions in a computer simulation of piriform cortex. J. Neurophysiol., 67: 981–995, 1992.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Alexander D. Protopapas
    • 1
  • James M. Bower
    • 1
  1. 1.Division of Biology, 216-76California Institute of TechnologyPasadena

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