Chloride Transport in the Squid Giant Axon

  • John M. Russell
  • Walter F. Boron


The squid giant axon has been the object of study by neurobiologists for almost 50 years. It arises in the stellate ganglion as the syncytial fusion of several hundred small axons arising from separate ganglionic cells. Depending upon the squid species of origin, the diameter of the giant axon can vary from 200 µm to 1500 µm. The most commonly used species, Loligo pealei and L. forbesi, have axons with diameters of 400–900 µM. The large size of the axon functionally serves to permit the rapid conduction of action potentials by reducing the electrical resistance of the axoplasm. Thus, the axon serves to rapidly transmit excitatory signals to the musculature of the mantle wall thereby permitting rapid escape or attack movements.


Giant Axon Dialysis Fluid Ehrlich Ascites Tumor Cell Exchange Flux External Fluid 
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Copyright information

© Springer Science+Business Media New York 1990

Authors and Affiliations

  • John M. Russell
    • 1
  • Walter F. Boron
    • 2
  1. 1.Department of Physiology and BiophysicsUniversity of Texas Medical BranchGalvestonUSA
  2. 2.Department of Cellular and Molecular PhysiologyYale University, School of MedicineNew HavenUSA

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