Twenty Years as a Chemist in a Positron Emission Tomography Center
Positron emission tomography (PET) can be used to track molecules in the human body, and thus determine in vivo regional blood flow, blood volume, ligand-receptor interactions, sugar or lipid metabolism, and so forth. PET can also be used to explore brain function during cognitive or drug-induced stimulation, and to observe compensatory responses following damage, or during numerous diseases. PET is an interdisciplinary technic combining physics, chemistry, pharmacy, physiology, medicine, computer science and mathematics. Using some examples, we should like to illustrate the role of the chemist in a PET center and the problems he is likely to encounter.
KeywordsPositron Emission Tomography AChE Activity Positron Emission Tomography Study Positron Emission Tomography Examination Carbamate Group
Unable to display preview. Download preview PDF.
- 2.S. Bonnot-Lours, C. Crouzel, C. Prenant and F. Hinnen, 1992, Carbon-11 labelling of an inhibitor of acetylcholinesterase: [HC]physostigmine. J. Lab. Compds Ratiopharm. XXXIII, 4, 277–284.Google Scholar
- 6.B. Tavitian, S. Pappata, A.M. Planas, A. Jobert, S. Bonnot-Lours, C. Crouzel and L. Di Giamberardino, 1993, In vivo vizualisation of acetylcholinesterase with positron emission tomography. Neuro. Report 4, 5, 535–538.Google Scholar