Locus-Coeruleus-Induced Enhancement of the Perforant-Path Evoked Potential
Norepinephrine (NE) iontophoresed in the dentate gyrus of anesthetized rat (Neuman and Harley, 1983) or superfused on the hippocampal slice (Lacaille and Harley, 1985; Stanton and Sarvey, 1986) produces a significant and reliable enhancement of the perforant-pathevoked population spike. This NE-induced enhancement of population spike amplitude can last for many minutes or hours.
KeywordsDentate Gyrus Locus Coeruleus Enhancement Effect Perforant Path Population Spike Amplitude
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