Long-Term Effects of Firing on Excitability of Hippocampal CA1 Neurons
Backfiring a hippocampal CA 1 cell by stimulation of its axon can, under certain circumstances, cause it to become less excitable to synaptic input (Dunwiddie and Lynch, 1978). We have investigated the basis of this lowered excitability.
KeywordsVertical Arrow Tungsten Wire Test Pulse Population Spike Population Spike Amplitude
Unable to display preview. Download preview PDF.
- Andersen P., Eccles, J. C., and Løyning, Y., 1964, Pathway of postsynaptic inhibition in the hippocampus, J. Physiol. (Lond.) 27: 608–619.Google Scholar
- Dunwiddie, T., and Lynch, G., 1978, Long-term potentiation and depression of synaptic responses in the rat hippocampus: Localization and frequency dependency, J. Physiol. (Lond.) 276: 353–367.Google Scholar