Advertisement

Stress, Cancer: Stress Modulation of the Metastatic Process

  • K. P. Balitsky
  • Yu. P. Shmalko
  • V. G. Pinchuk

Abstract

The interest in the problem of stress effect on the origination and development of metastases is guided by the dictates of the actual clinical situation: (1) Most oncologic patients die of metastases; (2) the tumoral process and its treatment (radiotherapy, intensive chemotherapy, surgical management) are associated with excessive stress loads, both physiological and psychoemotional.

Keywords

Stress Effect Stress Reaction Metastatic Spreading Tumor Removal Metastatic Process 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Balitsky, K.P., and Shmalko, Yu.P., 1983, Stress and tumor process, Eksp. Onkol. 5:7–14 (Russian).Google Scholar
  2. 2.
    Stone, J.P., Holtzman, S., and Shellabarger, G.J., 1979, Neoplastic responses and correlated prolactin levels in diethylstilbestrol treated ACI and SpraqueDawley rats, Cancer Res. 39:773–778.Google Scholar
  3. 3.
    Heuson, J.C., Legros, N., and Heimann, R., 1972, Influence of insulin administration on growth of the 7–12-dimethylbenz(a)anthracene induced mammary carcinoma in intact, oophorectomized and hypophysectomized rats, Cancer Res. 32:233–238.Google Scholar
  4. 4.
    Mittra, I., and Hayward, J.L., 1974, Hypothalamic-pituitary-thyroid axis in breast cancer, Lancet 7:885–889.Google Scholar
  5. 5.
    Balitsky, K.P. (ed.), 1983, Nervous System and Antitumor Protection,Naukova Dumka, Kiev (Russian).Google Scholar
  6. 6.
    Meerson, F.Z., Kogan, V.E., Primenko, L.D., et al.,1979, Activation of lipid peroxidation under emotional-pain stress, Byull. Eksp. Biol. Med. 88:404–406 (Russian).Google Scholar
  7. 7.
    Willis, E.D., 1971, Effect of lipid peroxidation on membrane-bound enzymes of endoplasmic reticulum, Biochem. J. 132:792–799.Google Scholar
  8. 8.
    Jensen, E.V., 1950, Free radicals, peroxides and antioxidants in some biological processes, in: Fifth Conf.Biol.Antioxidants Transact. Abstr. Volume 4, Macy, New York, p. 159.Google Scholar
  9. 9.
    Meerson, F.Z., 1981, Adaptation, Stress, and Prophylaxis,Nauka, Novosibirsk (Russian).Google Scholar
  10. 10.
    Mekler, L.B., 1978, Tumor induction mechanisms in general theory of carcinogenesis, Us. Sovrem. Biol. 85:135–152 (Russian).Google Scholar
  11. 11.
    Ader, R. (ed.), 1981, Psychoneuroimmunology,Academic Press, New York.Google Scholar
  12. 12.
    Balitsky, K.P., and Vinnitsky, V.B., 1981, The central nervous system and cancer, in: Stress and cancer, Hogrefe, Toronto, pp. 1–43.Google Scholar
  13. 13.
    Balitsky, K.P. (ed.), 1978, Antitumor Resistance Mechanisms,Naukova Dumka, Kiev (Russian).Google Scholar
  14. 14.
    Shmalko, Yu.,P., Smelkova M.I., and Vinnitsky, V.B., 1980, On the state of adrenal gland medulla in the course of experimental tumors development, Eksp. Onkol. 2:64–67 (Russian).Google Scholar
  15. 15.
    Devoyno, L.V., and Ilyuchenok, P.Yu., 1983, Monoaminergic Systems in Regulation of Immune Reactions, Nauka, Novosibirsk, ( Russian).Google Scholar
  16. 16.
    Newberry, B.H., 1981, PSS and the development of animal tumors, in: Perspectives on Behavioral Medicine (S.M. Weiss et al., eds), Academic Press, New York, pp. 329–439.Google Scholar
  17. 17.
    Kavetskii, R.E., Turkevich, N.M., and Balitsky, K.P., 1966, On the psycho-physiological mechanism of the organism’s resistance to tumor growth, Ann. N.Y. Acad. Sci. 125:933–945.Google Scholar
  18. 18.
    Nieburgs, H.E., Weiss, J., Navarrete, N., et al.,1976, Inhibitory and enhancing effects of various stresses on experimental mammary tumorigenesis, in: Third International Symposium on Detection and Prevention of Cancer: Program and Abstracts. Dekker, New York, p. 216.Google Scholar
  19. 19.
    Amkraut, A., and Solomon, G.F., 1972, Stress and murine sarcome virus (Moloney)-induced tumors, Cancer Res. 32:1428–1433.Google Scholar
  20. 20.
    Weiss, J.M., 1970, Somatic effects of predictable and unpredictable shock, Psychosom. Med. 32:397–408.Google Scholar
  21. 21.
    Desiderato, O., Wald, E.D., and Mackinon, J.R., 1973, Production of gastric ulcers in the unrestrained rat, Physiol Behay. 10:825–827.Google Scholar
  22. 22.
    Bammer, K., 1981, Stress, spread and cancer, in: Stress and Cancer, Hogrefe, Ioronto, pp. 137–164.Google Scholar
  23. 23.
    Sklar, L.S., and Anisman, H., 1981, Stress and cancer, Psychol. Bull. 89:369406.Google Scholar
  24. 24.
    Nieburgs, H.E., Navarette, M., Strax, P., et al.,1979, The role of stress in human and experimental oncogenesis, Cancer Detect. Prevent. 2:307–336.Google Scholar
  25. 25.
    Soifter, E., 1976, Effect of glucagon and insulin on the growth of cells in vitro, Science 193:74.Google Scholar
  26. 26.
    Solomon, G.F., and Amkraut, A.A., 1979, Neuroendocrine aspects of the immune response and their implications for stress effects on tumor immunity, Cancer Detect. Prevent. 2:197–224.Google Scholar
  27. 27.
    Gorelic, E., Segal, S., and Feldman, M., 1981, On the mechanism of tumor concomitant immunity, Int. J. Cancer 27:847–856.Google Scholar
  28. 28.
    Balitsky, K.P., Shmalko, K.P., Pridatko, O.E., and Smelkova M.I., 1984, Metastatic spreading and stress reactions in surgical removal of tumor, Eksp. Onkol. 6:45–47 (Russian).Google Scholar
  29. 29.
    Syromiatnikov, A.V., and Alistratov, A.V., 1984, Nervous pathways of stress influences in metastatic process, in: Fifth Symposium of the European Working Group for Psychosomatic Cancer Research (EUPSYCA), Kiev, p. 15. (Abstracts, Kiev, June 4–9, 1984.)Google Scholar
  30. 30.
    Sopotsinskaya, E.B., Fadeev, V.A., and Balitsky, K.P., 1984, Detection of key-Ions produced by tumor in blood serum of mice with metastatic Lewis carcinoma, Eksp. Onkol. 6:25–36 (Russian).Google Scholar
  31. 31.
    Vorontsova, A.L., Kudryavets, Yu.I., Fadeev, V.A., and Balitsky K.P., 1983, Antimetastatic effect of interferon in surgical removal of experimental tumors, Eksp. Onkol. 5:45–49 (Russian).Google Scholar
  32. 32.
    Nesterov, G.V., 1983, Effect of keylons on erythropoiesis, Usp. Sovrem. Biol. 95:84–89 (Russian).Google Scholar
  33. 33.
    Vorontsova, A.L., 1984, The influence of surgical stress on the interferon system, in: Fifth Symposium of the European Working Group for Psychosomatic Cancer Research (EUPSYCA), Kiev, p. 18. (Abstracts, Kiev, June 4–9, 1984.)Google Scholar
  34. 34.
    Umansky, Yu.A., Balitsky, K.P., and Andronati, S.A., 1982, Immunostimulating effect produced by some synthetic stimuli of immunity, in: Clinical Application of Zymosan and the Study of Its Action, RMI, Riga, pp. 173–177 (Russian).Google Scholar
  35. 35.
    Shmalko, Yu.P., 1984, Stress modulation of metastatic process, in: Fifth Symposium of the European Working Group for Psychosomatic Cancer Research (EUPSYCA), Kiev, p. 14. (Abstracts, Kiev, June 4–9, 1984.)Google Scholar
  36. 36.
    Archipov, S.A., 1982, Inhibitory effect of transplanted tumor upon the development of metastases into the lungs in mice, Vopr. Onkol. 28:44–46 (Russian).Google Scholar
  37. 37.
    Panin, L.E., 1983, Biochemical mechanisms of stress, Nauka, Novosibirsk, ( Russian).Google Scholar
  38. 38.
    Pinchuk, V.G., Balitsky, K.P., Shmalko, Yu.P., et al.,1983, Stress-induced damages of lung vessels and their effect upon the development of metastases in lungs, in: Modern Methods of Morphological Study in Theoretical and Applied Oncology.,Volume 2, Tbilisi, pp. 42–43 (Russian).Google Scholar
  39. 39.
    Pinchuk, V.G., Balitsky, K.P., and Shmalko, Yu.P., 1983, Secretoformation in adrenal medulla under conditions of metastatic stimulation, in: Eighth International Congress of Cytology, Abstracts, Quebec, part 3, p. 1098, Montreal, Canada, June 19–23, 1983.Google Scholar
  40. 40.
    Vasina, I.P., and Vasilchuk, O.A., 1982, Ultrastructural alterations in lungs in case of thermal trauma in experiment, Arch. Patol. 44:34–39 (Russian).Google Scholar
  41. 41.
    Hüker, H., Schafer, U., and Meinen, K., 1974, Early morphological alterations of the rat lung with increased intracranial pressure Virchows Arch. Pathol. Anat. Histol. 362: 331–342.Google Scholar
  42. 42.
    Komissarenko, V.P., Tronko, N.D., and Minchenko, A.G., 1982,Modern views on the mechanism of glucocorticoid hormones’ action, Physio.J. 28:721–733.Google Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • K. P. Balitsky
    • 1
  • Yu. P. Shmalko
    • 1
  • V. G. Pinchuk
    • 2
  1. 1.Department of Pathogenetic Mechanisms of Metastatic ProcessR. E. Kavetsky Institute of Oncology Problems of the Academy of Sciences of the UkrSSRKievUSSR
  2. 2.R. E. Kavetsky Institute of Oncology Problems of the Academy of Sciences of the UkrSSRKievUSSR

Personalised recommendations