A Microdosimetry Model for BNCT Analysis
The therapeutic effect of boron neutron capture therapy depends on the microscopic distribution of the boron atoms. A given macroscopic boron distribution can yield completely different therapeutic effects for different distributions of the boron atoms on a microscopic scale. In this work, a stochastic model for the subcellular dosimetry has been developed to calculate the effect of BNCT in tumour cells as well as in capillaries for different capture reactions and for proton recoil. The microdosimetry model calculates the dose distribution on a cellular scale, the probability functions of energy depositions in the cell nucleus (hit size curve) and the cell survival fractions.
KeywordsBoron Haas Rene
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