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Remodeling of the Heavy-Water Facility of the Kyoto University Reactor for Epithermal and Thermal Neutrons

  • Tooru Kobayashi
  • Yoshinori Sakurai
  • Keiji Kanda
  • Yoshiaki Fujita

Abstract

It is very important for Neutron Capture Therapy (NCT) to get sufficient thermal neutron fluence at the tumor part without exceeding the tolerance dose of normal tissue. For the purpose of increasing the curable efficacy for a deep-seated tumor, it is necessary to increase the ratio of thermal neutron flux at the tumor to that at the surface. In the current thermal neutron irradiation for NCT, it is not sufficient to attain the suitable thermal neutron flux distribution in patient with deep-seated tumor over 5 cm depth. The following four methods have been considered to improve the thermal neutron flux distribution for NCT:
  1. 1.

    to adjust the forward directional components of neutron beam,1

     
  2. 2.

    to make a void in a human body,2

     
  3. 3.

    to replace partially natural body water (i.e. light water) with heavy water,3 and

     
  4. 4.

    to control the energy spectrum of the incident neutron beam.4

     

Keywords

Thermal Neutron Heavy Water Relative Biological Effectiveness Thermal Neutron Flux Epithermal Neutron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Tooru Kobayashi
    • 1
  • Yoshinori Sakurai
    • 1
  • Keiji Kanda
    • 1
  • Yoshiaki Fujita
    • 1
  1. 1.Research Reactor InstituteKyoto UniversityKumatori-cho, Sennan-gun OsakaJapan

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