The Boron Neutron Capture Therapy Research Facility at the Tehran Research Reactor (TRR)

  • M. K. Marashi
  • A. Pazirandeh


In this paper, the procedure applied to produce a neutron beam suitable for Boron Neutron Capture Therapy (BNCT) research at the Tehran Research Reactor (TRR) is discussed. In this project the reactor core of the Nuclear Research Center of the Atomic Energy Organization of Iran was used as the neutron source. The neutron energy spectrum in the reactor core and in the neutron beam tube was calculated using two-dimensional transport code DOT-3 and also measured by using the foil activation technique unfolded by the code SAND-II.

Our calculations showed that the neutron energy suitable for BNCT should be less than 10kev. In order to obtain neutrons in this energy range a neutron filter made of aluminium and iron in an aluminium casing was used which produces a neutron energy spectrum in the low key region. To eliminate the core gamma rays and induced capture gamma rays of the filter materials, a gamma shield made of bismuth block was used. Since the neutron beam emerging from the filter is rather scattered, to narrow it further a neutron collimator made of lead and concrete was designed, constructed and then inserted into the neutron beam tube.


Neutron Energy Neutron Beam Boron Neutron Capture Therapy Reactor Core Neutron Energy Spectrum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    H. Hatanaka, et al, Clinical experiences of boron neutron capture therapy for gliomas: A comparison with conventional chemo-immuno radiotherapy, in “Boron Neutron Capture Therapy for Tumors,” H. Hatanaka, ed., Nishimura Co. Ltd., Niigata, Japan, 1986, pp. 349–78.Google Scholar
  2. 2.
    G. Constantine, et al, Progress towards boron neutron capture therapy at Harwell, In: “Multipurpose Research Reactor Conference,” held at Grenoble, France, 1987.Google Scholar
  3. 3.
    R.F. Barth, et al, Boron neutron capture therapy for cancer, Cancer, 70–12, 1992.Google Scholar
  4. 4.
    B.V. Harrington, Optimization of an epithermal beam in HIFAR for boron neutron-capture therapy, Australian Nuclear Science and Technology Organization, ANSTO/E662, August 1987.Google Scholar
  5. 5.
    M.K. Marashi, A. Pazirandeh, The effect of incident neutron energy and tumor in BNCT study, In: “Advances in Neutron Capture Therapy,” A.H. Soloway, ed., Plenum Press, New York, pp. 191–95, 1993.CrossRefGoogle Scholar
  6. 6.
    M.K. Marashi, PhD. Thesis, Amir Kabir Technical University, 1994.Google Scholar
  7. 7.
    Y. Oka, et al, A design study of the neutron irradiation facility for boron neutron capture therapy, Nucl. Tech., 55: 642, 1981.Google Scholar
  8. 8.
    D.J. Noonan, et al, Biological studies of an epithermal beam for NCT with Na2B’2H I’ SH., In: “Proc. First Int. Symp. on Neutron Capture Therapy,” BNL-51730, 1983, p. 315.Google Scholar
  9. 9.
    R.M. Brugger, et al, An epithermal neutron beam for neutron capture therapy at the Missouri University Research Reactor, Nucl. Tech., 98, 1992.Google Scholar
  10. 10.
    W.A. Rhoades, F.R. Myatt, The DOT-III Two-Dimensional Discrete Ordinate Transport Code, ORNLTM-4280, 1973.Google Scholar
  11. 11.
    M.K. Marashi, et al, I RAN.LIB (Improved Range of ANISN/PC Library): A P3 coupled neutron-gamma cross section library in ISOTXS format to be used by ANISN/PC (CCC-0514/02), Ann. Nucl. Energy, 18–10: 597–602, 1991.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • M. K. Marashi
    • 1
  • A. Pazirandeh
    • 2
  1. 1.Nuclear Research CenterAtomic Energy Organization of IranTehranIran
  2. 2.Physics DepartmentUniversity of TehranTehranIran

Personalised recommendations