Antineoplastic Agents and Cancer Cell Differentiation
Because specific approaches for the inhibition or modulation of the cancer cell are lacking, therapies are used that adversely affect some normal cells as well as tumor cells. These treatments make use of highly cytotoxic antibiotics such as daunomycin and actinomycin D, and of cytotoxic antimetabolites such as methotrexate and araC. The agents are employed at maximally tolerated doses in order to remove the greatest possible number of tumor cells.
KeywordsLeukemia Cell Antineoplastic Agent Myeloid Leukemia Cell Tumor Cell Population Microbial Metabolite
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