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Coccal Cell Switching and the Survival and Virulence of C. jejuni at High Oxygen Tensions

  • Philippa Harvey
  • Catherine Fearnley
  • Diane Newell
  • Michael Hudson
  • Stephen Leach

Abstract

Campylobacter jejuni is a microaerophile which demonstrates oxygen-dependant growth1 although atmospheric levels of oxygen are usually damaging. Under favourable conditions cell morphology is spiral but in stressful environments the cells often become coccoid in appearance. Reasons for this change have been investigated previously and thought to include light, medium components, and atmospheric oxygen tension. Moran2 proposed that toxic oxygen derivatives in the culture may trigger coccoid formation. The viability of these cells has been widely investigated using a variety of techniques, and these have variously suggested that the coccoids may be a degenerative or alternatively a dormant state.

Keywords

Dilution Rate Invasion Assay Carbon Limitation High Oxygen Tension United Kingdom Introduction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Hodge J.P and Krieg N.R (1994) J. App. Bacteriol., 77, 666–673.CrossRefGoogle Scholar
  2. 2.
    Moran A.P. and Upton M.E. (1987) J. App. Bacteriol., 62, 527–537.CrossRefGoogle Scholar
  3. 3.
    Rodriguez G, Philpps D, Ishiguro and Ridgway H.F (1992) App. & Environ. Microbiol. 58, 1801–1808.Google Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Philippa Harvey
    • 1
  • Catherine Fearnley
    • 2
  • Diane Newell
    • 2
  • Michael Hudson
    • 1
  • Stephen Leach
    • 1
  1. 1.Bacterial Pathogenesis Section, Research DivisionCentre of Applied Microbiology and ResearchSalisbury, WiltshireUK
  2. 2.Applied and Molecular Immunology UnitCentral Veterinary Laboratory (Weybridge)Addlestone, SurreyUK

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