Molecular Characterization of Campylobacter Virulence Genes

A 36-kDa Lipoprotein Able to Convert Escherichia coli to a Haemolytic Phenotype and with Homology to Siderophore-Binding Proteins
  • S. F. Park
  • P. T. Richardson


Pathogenicity in campylobacters remains poorly defined, especially at the genetic level, where few genes encoding virulence factors have been characterised. The role toxins play in campylobacter pathogenesis is equivocal but some strains of Campylobacter jejuni and C. coli are haemolytic on blood plates and in contact assays. This haemolytic activity may play a role in pathogenesis as it does for many other species.


Iron Uptake Blood Agar Plate Iron Acquisition Haemolytic Activity Periplasmic Binding Protein 


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  1. 1.
    Dickinson J.H., Grant K.A. and Park S.F. (1995) Curr. Microbiol, 31, 92–96.PubMedCrossRefGoogle Scholar
  2. 2.
    Gomez A., Ramon D. and Sonz P. (1994) Microbiol (Reading) 140, 1839–1845.CrossRefGoogle Scholar
  3. 3.
    Koster W.L., Actis L.A., Waldbeser M.E., Tolmasky M.E. and Crosa J.H. (1991) J. Biol. Chem, 266, 23829–23833.PubMedGoogle Scholar
  4. 4.
    Park S.F. and Richardson P.T.(1995) J.Bacteriol. 177, 2259–2264.PubMedGoogle Scholar
  5. 5.
    Richardson P.T. and Park S.F.(1995) Microbiol, in press.Google Scholar
  6. 6.
    Weinberg E.D.(1995) In: Virulence Mechanisms of Bacterial Pathogens 2nd Edition. Eds. Roth J.A., Bolin CA., Brogden K.A., Minion C.F. and Wannemuehler M.J. ASM Press, Washington. DC Chapter 6 79–93.Google Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • S. F. Park
    • 1
  • P. T. Richardson
    • 1
  1. 1.Institute of Food ResearchReading LaboratoryReadingUK

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