ABO, Hh, Lewis, and Secretion

Serology, Genetics, and Tissue Distribution
  • Rafael Oriol
Part of the Blood Cell Biochemistry book series (BLBI, volume 6)


ABO, the major red cell alloantigen system, was discovered by Landsteiner (1901) testing the agglutination of normal erythrocytes by serum from different individuals. His tests showed that individuals with A antigen on erythrocytes have anti-B antibodies in serum. People with B antigen on red cells have anti-A in serum. Persons devoid of A and B antigens on red cells (blood group zero or O) have both anti-A and anti-B, and AB individuals with both antigens on red cells have no natural anti-A or anti-B.


Blood Group Lewis Antigen Precursor Chain Lewis Blood Group Fucosyltransferase Gene 
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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Rafael Oriol
    • 1
  1. 1.Unité de Recherche U178 de l’Institut National de la Santé et de la Recherche Médicale (INSERM)Villejuif CedexFrance

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