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Heterogeneity of Mononuclear Phagocytes

An Interpretive Review
  • Pieter J. M. Leenen
  • Priscilla A. Campbell
Part of the Blood Cell Biochemistry book series (BLBI, volume 5)

Abstract

In this chapter we would like to review evidence supporting the concept that there is extensive heterogeneity of mammalian mononuclear phagocytes. Given the limits of this chapter, we will summarize data supporting this notion rather than provide an in-depth review of particular characteristics and functions of these cells. Therefore, the main subjects will be the mononuclear phagocyte system as a whole and the heterogeneous features of the various members of the system expressed both phenotypically and functionally. Finally, we will discuss various models that may explain how mononuclear phagocyte heterogeneity is generated (see also Chapter 3, this volume).

Keywords

Migration Inhibitory Factor Mononuclear Phagocyte Bone Marrow Culture Mononuclear Phagocyte System Milky Spot 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Pieter J. M. Leenen
    • 1
  • Priscilla A. Campbell
    • 2
    • 3
  1. 1.Division of Basic Immunology, Department of MedicineNational Jewish Center for Immunology and Respiratory MedicineDenverUSA
  2. 2.Division of Basic Immunology, Department of MedicineNational Jewish Center for Immunology and Respiratory MedicineDenverUSA
  3. 3.The Department of Pathology, the Department of Microbiology and Immunology and The Cancer CenterUniversity of Colorado Health Science CenterDenverUSA

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